The Relation between Type One Diabetes Mellitus and Occurrence of Celiac Disease in Patients with in Babylon Teaching Hospital for Maternity and Children

Abstract

Although the association between type 1 diabetes mellitus and celiac disease is well known, the presenting
features and clinical characteristics of the two diseases, when they coexist, are less well documented so
the study aimed to Estimate the incidence of celiac disease among patients attended to diabetic clinic in
the Babylon maternity and pediatric teaching hospital. Include retrospective study involves patients with
T1DM attending the pediatric diabetic clinic in the Babylon maternity and pediatric teaching hospital, were
screened for celiac disease by serological testing for celiac antibodies (tissue transglutaminase). Control
group without diabetes mellitus were also been evaluated. The control group are those who were admitted to
the hospital for other diseases like gastroenteritis or chest infection, have no past medical history or chronic
illnesses, and have no diabetes mellitus neither symptoms nor abnormal blood investigation results. Of the
50 patients with T1DM and 50 without diabetes mellitus, 3 patients (6%) of the study group tested were
antibody positive. Celiac disease presented atypically in the majority of cases with an unpredictable interval
between diagnosis of diabetes and celiac disease presentation. In this study, we found that patients with
classical symptoms of celiac disease, (diarrhea, anorexia, abdominal distension, foul smelling stool, short
stature, unexplained hypochromic anemia), may have negative screening for celiac disease, while those with
positive screening test, were asymtomatic.