Seroprevalence of BKV-Antibodies among Cancer Patients and Healthy Individuals

Authors

  • Vian Ibraheem Husain
  • Salah Mahdi Hassen
  • Amal Aziz Kareem

DOI:

https://doi.org/10.37506/ijfmt.v15i4.16764

Keywords:

BK polyomavirus, seroprevalence, cancer, ELISA, Kirkuk.

Abstract

BKPyV, a small DNA virus classified into the polyomaviridaefamily, is holoendemic with global distribution
among human population.The objective of this study is to determine the prevalence of anti-BK polyomavirus
IgG antibodies among cancer patients and healthy controls. In the present study, A total of 85 serum samples
were collected (65 cancer patients and 20 healthy controls) with age range between 15- 75 years, the femaleto-
male ratio was 3:1. All obtained sera samples were tested using ELISA method for the detection of
anti-BK polyomavirus IgG antibodies. BKV-IgG seroprevalence show high rate of exposure to the virus
48.23% (41 of 85 samples) revealed positive result (50.77% in cancer patient and 40% in healthy control).
Seroprevalence was not different between female and male. The frequency of IgG antibodies decreased from
66.67% in the age group <40 years to 46.94% among age group 40-60 years, and drop again to 38.1% in
>60 years old.

Author Biographies

Vian Ibraheem Husain

Msc Student, Health and Medical Technical College, Kirkuk. Northern Technical University

Salah Mahdi Hassen

Assistance Professor, College of Health and Medical Technology\Baghdad. Middle Technical University

Amal Aziz Kareem

Assistance Professor, College of Health and Medical Technology\Baghdad. Middle Technical University

Published

2021-08-16

How to Cite

Vian Ibraheem Husain, Salah Mahdi Hassen, & Amal Aziz Kareem. (2021). Seroprevalence of BKV-Antibodies among Cancer Patients and Healthy Individuals. Indian Journal of Forensic Medicine & Toxicology, 15(4), 578-282. https://doi.org/10.37506/ijfmt.v15i4.16764