Impact of COVID-19 on Multiple Body Organ Failure: A Review

Authors

  • Aya Yaseen Mahmood Alabdali
  • Sasikala Chinnappan
  • Basma M. Abd Razik
  • Mogana R
  • Shaik Ibrahim Khalivulla
  • Rahman H

DOI:

https://doi.org/10.37506/ijfmt.v15i4.16808

Keywords:

Corona Virus disease (COVID-19), Organ failure, SAR-CoV-2, Cardiovascular System, Kidney, Lungs.

Abstract

COVID-19 is a highly contagious disease caused by Severe Acute Respiratory Syndrome CoronaVirus-2
(SARS-CoV-2) which is a novel single-stranded positive RNA infection which consist of cytokines that
activate the pathogenic systems that cause high respiratory pain condition and adversely effect on multiple
body organ in humans as per their immunity standards to fight against the virus. SARS-CoV-2 enters the
host cell through Angiotensin-Converting Enzyme 2 (ACE 2). ACE 2 is a sub-part of the Renin-Aldosterone
Angiotensin System (RAAS) which is intelligently communicated in the kidney, heart, lungs and fatal tissues
of the body. The malfunctioning of RAAS in the body leads to hypertension, cardiovascular sicknesses,
endocrine system and also affect negatively a brain body communication channel. Treatments on the RAAS
structure, thiazolidinedione’s and smoking, toxaemia, kidney, lungs disorder due to the SARS-CoV-2 attack
on the host cell and notice the behavioural changes of body organs on the arrival of cytokines that causes
multi-organ damage. This paper involves the study of the effects of coronavirus disease on multiple bodyorgan
damages.

Author Biographies

Aya Yaseen Mahmood Alabdali

Assistant Lecturer Faculty of Pharmaceutical Sciences/ UCSI University Kuala Lumpur, Malaysia. Collage
of Pharmacy/ The University of Mashreq, Iraq, Baghdad

Sasikala Chinnappan

Assistant Professor/ Faculty of Pharmaceutical Sciences/ UCSI University Kuala Lumpur, Malaysia,

Basma M. Abd Razik

Assistant Professor/ College of Pharmacy/Mustansiriyah University, 10001, Baghdad, Iraq

Mogana R

Associate Professor/ Faculty of Pharmaceutical Sciences/UCSI University Kuala Lumpur, Malaysia

Shaik Ibrahim Khalivulla

Assistant Professor/ Faculty of Pharmaceutical Sciences/ UCSI University Kuala Lumpur, Malaysia,

Rahman H

Assistant Professor/ Faculty of Pharmaceutical Sciences/ UCSI University Kuala Lumpur, Malaysia,

Published

2021-08-16

How to Cite

Aya Yaseen Mahmood Alabdali, Sasikala Chinnappan, Basma M. Abd Razik, Mogana R, Shaik Ibrahim Khalivulla, & Rahman H. (2021). Impact of COVID-19 on Multiple Body Organ Failure: A Review. Indian Journal of Forensic Medicine & Toxicology, 15(4), 835-844. https://doi.org/10.37506/ijfmt.v15i4.16808

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