Increased Corticosterone Levels due to Chronic Stress Reduces IGF-II Expression in Rattus norvigecus

Authors

  • Ade Septiari Rahman
  • Reny I’tishom
  • Ashon Sa’adi

DOI:

https://doi.org/10.37506/ijfmt.v15i4.16827

Keywords:

Corticosterone, Chronic Stress

Abstract

The optimal folliculogenesis process describes a good condition of the female reproductive system.
One of the main growth factors in the folliculogenesis is IGF-II which is important for proliferation and
differentiation of granulosa cells and also steroidogenesis. Chronic stress can cause ovulation failure and
folliculogenesis disorders. Increased corticosterone levels due to chronic stress will cause disruption in the 

Author Biographies

Ade Septiari Rahman

Master Degree of Reproductive Health Science Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia

Reny I’tishom

Lecturer in Department of Medical Biology Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia

Ashon Sa’adi

Lecturer and Consultant in Department of Obstetrics and Gynecology Faculty of Medicine Universitas Airlangga/ Dr. Soetomo General Hospital, Surabaya, Indonesia

Published

2021-08-16

How to Cite

Ade Septiari Rahman, Reny I’tishom, & Ashon Sa’adi. (2021). Increased Corticosterone Levels due to Chronic Stress Reduces IGF-II Expression in Rattus norvigecus. Indian Journal of Forensic Medicine & Toxicology, 15(4), 188-192. https://doi.org/10.37506/ijfmt.v15i4.16827

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