Visfatin and Correlated Clinical parameters in Type 2 Diabetes Mellitus as Diagnostic Factor in Osteoarthritis Patients in Sulaimani, Iraq
Keywords:Visfatin, Type 2, Diabetes mellitus, Neuropathy, Osteoarthritis.
It was proved that neuropathy caused by impaired glucose tolerance / diabetes mellitus inhibits the expression
of pain due to osteoarthritis in the lower extremities among a portion of patients displaying radiographic
osteoarthritis. Both osteoarthritis and DM can be viewed as chronic disease processes characterized by
earl, undetected levels of biological change. This study was carried out to investigate serum visfatin and
correlated to parameters in osteoarthritis patients. Sixty-eight patients suffering from Diabetes Mellitus and
osteoarthritis are involved in the study for investigating the role of visfatin and related clinical markers in the
cases studied. Twenty healthy controlled volunteers were used for comparing obtained results. Specific kits
were used for the determination of visfatin and related parameters. The results of the study were revealed
increases in the levels of visfatin, glucose, HbA1c, and insulin resistant. The only decreases were found in
the insulin levels. It seems that visfatin has been proved to have a physiological influence in osteoarthritis is
Patients suffers from type II diabetes mellitus.
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