The effect of oxidative stress on vitiligo patients

Abstract

The purpose of the study to shed light on one of the hypotheses keys in causing disease vitiligo is the
stress hypothesis of oxidative, stable of vitiligo have been identified active stages or on the basis of the
development or the emergence of new spots in the past three months and the absence of new or patches
development in the past six months, the in a row, this study included three groups, all of them were male.
The first group included the active group, patients with vitiligo of the active type30 the second person, the
dormant group, includes static type vitiligo patients 25One person, the third, the control group (apparently
healthy) included20People. We have examined the serum levels of Superoxide Dismutase enzyme, catalase
enzyme, and Malondi- aldehyde, our results revealed that the level of higher than Malondi- aldehyde at the
level of probability (P <0.05) In the serum of the disease group compared to the control group, a significant
increase in the activity of superoxide dismutase was observed in the serum of the disease group at the level of
probability(P <0.05)Compared to the control group, the catalase activity decreased at the probability level(
P <0.05) In the pathological group compared with the control group, our study shows that stress Oxidative
has a role in the physiology pathogenesis of vitiligo active and static. An imbalance of antioxidants was
observed in the blood of active Vitiligo patients.