The Effect of COVID-19 on Blood Pressure Control in Hypertension Patients– A Literature Review

Authors

  • Raditya Manusakti
  • Judya Sukmana
  • Wachjudi Kurniaj
  • Liliawanti

DOI:

https://doi.org/10.37506/ijfmt.v15i4.17035

Keywords:

ACE2, Blood Pressure Control, Comorbidity, COVID-19, Hypertension, RAAS.

Abstract

COVID-19 is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2). First identified
in Wuhan, China, in December 2019, and declared an International Public Health Emergency in January
2020, the WHO declared a pandemic in March 2020. Hypertension, a disease that has long been a problem
for most people in Indonesia and around the world . COVID-19 can affect blood pressure control for people
with hypertension due to obstruction of the RAAS system. This research was conducted to find out what
effect COVID-19 has on blood pressure control in people with hypertension. In the condition of COVID-19
patients with comorbid hypertension, SARS-CoV-2 which attacks ACE2 can eliminate the role of ACE2 in
the RAAS system. Inhibition of ACE2 can also cause buildup of angiotensin II which has a vasoconstrictive
effect. This results in the absence of homeostasis in the blood pressure control system and makes blood
pressure conditions that continue to be at high pressure.

Author Biographies

Raditya Manusakti

Student at Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia

Judya Sukmana

Lecturers and Master of Patobiologi at Faculty of Medicine Hang Tuah University, Surabaya, Indonesia

Wachjudi Kurniaj

Lecturers at Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia

Liliawanti

Lecturers at Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia

Published

2021-08-16

How to Cite

Raditya Manusakti, Judya Sukmana, Wachjudi Kurniaj, & Liliawanti. (2021). The Effect of COVID-19 on Blood Pressure Control in Hypertension Patients– A Literature Review. Indian Journal of Forensic Medicine & Toxicology, 15(4), 2213-2221. https://doi.org/10.37506/ijfmt.v15i4.17035