The Effect of COVID-19 on Blood Pressure Control in Hypertension Patients– A Literature Review
Keywords:ACE2, Blood Pressure Control, Comorbidity, COVID-19, Hypertension, RAAS.
COVID-19 is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2). First identified
in Wuhan, China, in December 2019, and declared an International Public Health Emergency in January
2020, the WHO declared a pandemic in March 2020. Hypertension, a disease that has long been a problem
for most people in Indonesia and around the world . COVID-19 can affect blood pressure control for people
with hypertension due to obstruction of the RAAS system. This research was conducted to find out what
effect COVID-19 has on blood pressure control in people with hypertension. In the condition of COVID-19
patients with comorbid hypertension, SARS-CoV-2 which attacks ACE2 can eliminate the role of ACE2 in
the RAAS system. Inhibition of ACE2 can also cause buildup of angiotensin II which has a vasoconstrictive
effect. This results in the absence of homeostasis in the blood pressure control system and makes blood
pressure conditions that continue to be at high pressure.
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