Correlation of High sensitivity C-reactive Protein Levels with Body Mass Index in a Group of Adults in Erbil City

Authors

  • Salam Naser Zangana
  • Namir G Al-Tawil
  • Suhad Ali Khazaal

DOI:

https://doi.org/10.37506/ijfmt.v15i4.17061

Keywords:

High sensitivity C-reactive protein, Body mass index, Obesity.

Abstract

Background and Objectives: The prevalence of overweight and obesity is increasing worldwide. Obesity
is related to morbidity and mortality. High sensitivity C - reactive protein (hs-CRP) is an important
inflammatory marker to predict cardiovascular diseases. This study aims to correlate between hs-CRP levels
and BMI among healthy adults.
Materials and Methods: A cross-sectional study was conducted on 200 healthy adults from May 2019 to
October 2019. The study population was divided into four groups based on BMI; normal, overweight, obese
I, and obese II. Hs-CRP level was measured in all groups. Multiple linear regression analysis was done to
find out the independent factors affecting hs-CRP.
Results: Out of 200 participants, 56 (28%) had normal BMI, 43(21.5%) were overweight, 57(28.5%) were
obese group I and 44 (22%) were obese group II. The mean hs-CRP of the normal weight and overweight
participants was 1.03 mg/dl and 1.37 mg/dl respectively (p= 0.725), then there was a marked increase to
3.75 mg/dl and 7.69 mg/dl among the obese I and obese II participants respectively (p < 0.001). A positive
significant correlation was found between the hs-CRP levels and the BMI (r = 0.436, p < 0.001). The only
factor that was independently associated with the high hs-CRP was the BMI (B = 0.357, p < 0.001).
Conclusion: Rising BMI was significantly correlated with hs-CRP. The higher the BMI, the higher will
be plasma hs-CRP levels, suggesting the presence of chronic systemic inflammation which might lead to
cardiovascular events in the future.

Author Biographies

Salam Naser Zangana

Assistant Professor and Consultant Physician, Hawler Medical University. College of Medicine. Department
of Medicine. Erbil, Iraq

Namir G Al-Tawil

Professor of Community Medicine. Hawler Medical University. College of Medicine.Department of Community Medicine. Erbil

Suhad Ali Khazaal

Specialist in Family Medicine. Ministry of Health-Directorate of Health-Kurdistan region. Erbil, Iraq

Published

2021-08-16

How to Cite

Salam Naser Zangana, Namir G Al-Tawil, & Suhad Ali Khazaal. (2021). Correlation of High sensitivity C-reactive Protein Levels with Body Mass Index in a Group of Adults in Erbil City. Indian Journal of Forensic Medicine & Toxicology, 15(4), 2379-2388. https://doi.org/10.37506/ijfmt.v15i4.17061