Important of Morphological Examination of Bone Marrow for a Hematological and Non-Hematological Disorder

Abstract

Background: The bone marrow examination is important for the investigation, diagnosis, and management
of the blood, bone marrow and many systemic disorders. Morphological Bone marrow examination alone is
sufficient to diagnose nutritional anemias and most acute leukemia.
This study aimed to determine the importance of morphological examination of bone marrow to diagnose
hematological and non-hematological disorders like various systemic illnesses that affect the bone marrow.
Methods: A prospective study carried out for one year at the Hematology lab, Ninava Ibn Sena Teaching
Hospital, A total of 201 cases were investigated. The bone marrow examination was taken from the posterior
superior iliac spine.
Results: The age range was (15-87) years. The male-to-female ratio was 1:1.2. The most common disorder
finding was acute leukemia 17% (include AML & ALL) and AML is more common than ALL, whereas
lymphoproliferative disorders was second bone marrow finding fallowed by Megaloblastic anemia of
Myeloid dysplasia syndrome (MDS) and Essential thrombocythemia (ET).
Conclusion: Morphological bone marrow examination is a useful procedure in ascertaining the diagnosis of
several hematological and non-hematological disorders.