Changes in the Cancer Antigen Markers in the Pleural Liquid During Chemotherapy among Ovarian Cancer Patients

Abstract

The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in the
modern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancer
patients, objective of this report was to assess the effects of the first round of chemotherapy among women
with ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after the
chemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use in
deciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and post
platinum chemotherapy session demonstrated wide range of biochemical and protein marker changes among
ovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it is
proposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic tools
for ovarian cancer.