Assessment of Metabolic Profile in Relation with Polycystic Ovary Syndrome

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrinopathy that, by the most strict definition, affects
5 to 10% of women of reproductive age. There is not complete consensus about the definitive criteria for
the diagnosis of PCOS, which necessitates the searching for new biomarkers for definitive diagnosis.This
study is a case/control study carried on one hundred (100) women divided into two groups: 50 women with
PCOS, and 50 women were with absent features of PCOS represent a control group who were attending
the outpatient clinic of Gynecology department at Baghdad Teaching Hospital during the period from
March to September, 2018. A fasting blood sample was obtained from all women during the early follicular
phase (days 2–4 of the spontaneous cycle). Lipid profile, fasting blood glucose and fasting blood insulin,
luteinizing hormone (LH), follicular stimulating hormone (FSH), and testosterone were analyzed by immune
chemiluminescence method. There were no significant differences between the two groups regarding total
cholesterol, low density lipoprotein -cholesterol, high density lipoprotein -cholesterol and fasting blood
glucose. On the other hand, PCOS patients showed higher serum concentration of triglycerides and insulin
resistance than controls.