Malaria Infection Effect to Haemoglobin and Haematocrit in Pregnant Mus Musculus

Authors

  • Istiana
  • Widya Nursantari
  • Edi Hartoyo
  • Meitria Syahadatina Noor

DOI:

https://doi.org/10.37506/ijfmt.v16i1.17568

Keywords:

Hb, Ht, malaria, pregnant.

Abstract

Malaria is a disease that is caused by Plasmodium Sp. And infected by Anopheles mosquitos. Kalimantan
is one of endemic places for malaria. Prevalence of malaria is 2-76% depent to the places.Effect of
malaria to pregnant women can be anemia, renal failure, cerebral oedema and death. Prevamence of
anemia because of malaria in pregnant women is about 3-15%. This research was done by using animal
model to show malaria in pregnant. Goal of this research was to analyze malaria infection effect to
haemoglobin and haematocrit in pregnant Mus musculus. Research design was experimental using
posttest only with control group design. It consisted of K0 for control (20 samples) and K1 for infected
group (19 samples).Pregnant Mus musculus was injected P. berghei to infect plasmodium using 0,2 ml
infected serum intraperioteal in the first day of pregnant. Mus musculus was terminated in 19th day of
pregnant and took cardial blood to examine Hb and Ht of pregnant Mus musculus.The result was Hb
level mean for K0= 12,69 gr/dl and K1=12,832 dr/dl. Mean of Ht for K0=38,070% and K1=38,495%.
Statistical anayzes used U-Mann Whitney test, with p value for Hb level was 0,574 and Ht was 0,574.
The conclusion was malaria infection could not effect yet to Hb dan Ht level in pregnant Mus musculus.

Author Biographies

  • Istiana

    Department of Parasitology and Microbiology,  Faculty of Medicine, Lambung Mangkurat University

  • Widya Nursantari

    Department of Public Health,  Faculty of Medicine, Lambung Mangkurat University

  • Edi Hartoyo

    Department of Pediatric, Faculty of Medicine, Lambung Mangkurat University

  • Meitria Syahadatina Noor

    Department of Pediatric, Faculty of Medicine, Lambung Mangkurat University

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Published

2021-11-30

How to Cite

Malaria Infection Effect to Haemoglobin and Haematocrit in Pregnant Mus Musculus. (2021). Indian Journal of Forensic Medicine & Toxicology, 16(1), 655-657. https://doi.org/10.37506/ijfmt.v16i1.17568