Comparative Evaluation of Dexmeditomidine & Fentanyl in Terms of Cardiovascular Stress Response During Anesthetic Airway Management in Major Surgical Procedures

Authors

  • Niraj Rathod
  • Sunil Valand
  • Seema Rawat
  • Komal Makwana

DOI:

https://doi.org/10.37506/ijfmt.v16i1.17612

Keywords:

Airway management, Anaesthesia, cardiovascular stress, Dexmedetomidine, inflammatory mediators, fentanyl

Abstract

Background- airway management both in operation theatre and during emergencies remains challenge because of cardiovascular stress response & inflammatory mediators during procedure exhilarating the stress response itself leading to catastrophic events. This study is aimed to evaluate comparative efficacy of dexmedetomidine over fentanyl because of it have not only as sympatholytic also as anti-inflammatory properties. Study was orchestrated at tertiary care centre in western India after approval of institutional scientific & ethical committee. Methodology Study group include 50 patients of either sex aged between 18 to 55 years who were admitted for major surgical procedure and given consent for inclusion. Study group divided in two group for record & statistical analysis of parameters like heartrate, mean arterial pressure at various interval during surgery to ascertain the superiority of dexmedetomidine vs fentanyl in stabilizing cardiovascular stress response.

Author Biographies

Niraj Rathod

Assistant Professor, SBKS Medical Institute & Research Centre, Waghodiya, Pipariya, Gujarat,India

Sunil Valand

Assistant Professor, SBKS Medical Institute & Research Centre, Waghodiya, Pipariya, Gujarat,India

Seema Rawat

Professor, C.U. Shah Medical College and Hospital Dudhrej Rd, Laxminarayan Society, Surendra Nagar, Gujarat India

Komal Makwana

Assistant Professor, GMERS Medical College Gotri, Old TB hospital Campus, Gotri Rd, Gotri, Vadodara, Gujarat India

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Published

2021-11-30

How to Cite

Niraj Rathod, Sunil Valand, Seema Rawat, & Komal Makwana. (2021). Comparative Evaluation of Dexmeditomidine & Fentanyl in Terms of Cardiovascular Stress Response During Anesthetic Airway Management in Major Surgical Procedures. Indian Journal of Forensic Medicine & Toxicology, 16(1), 900–907. https://doi.org/10.37506/ijfmt.v16i1.17612