The Role of Oxidative Stress and Vitamin D in Aborted Women with Cytomegalovirus
Keywords:Abortion, Cytomegalovirus, Vitamin D, Malondialdehyde, Ceruloplasmin and Transferrin.
Abortion is one of the commonest reasons for acute presentation to gynecologists, recurrent spontaneous
abortion due to maternal infections transmissible in uterus at various stage of gestation can be caused
by a wide array of organisms including cytomegalovirus. This study included (25) aborted women, (25)
non- aborted women with cytomegalovirus seropositive test as a patients groups and (25) non- aborted
women with cytomegalovirus seronegative test as a control group. The study was designed to evaluate the
concentration of malondialdehyde (MDA) as an oxidative stress marker, the concentration of ceruloplasmin
(Cp) and transferrin (Tf) as an antioxidant marker and total vitamin D in cytomegalovirus infected women
and investigate the relation between oxidative stress and total vitamin D. The results show a significant
decrease in levels of serum MDA in aborted group with CMV in comparison to non-*-aborted and control
groups (p> 0.05), serum ceruloplasmin and transferrin significantly decrease in aborted group in contrast to
non-aborted and control groups (p > 0.05) and total vitamin D was decreased in all study groups but there
was a significant difference between studied groups (p > 0.05). The results of this study show disorder in
levels of (MDA, Cp, Tf and VD) aborted group with cytomegalovirus.
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