Study of in Vitro Antimicrobial Activity and in Vivo Wound Healing Potentiality of Leaves of Callistemon Viminalis

Authors

  • Avijit Mazumder
  • Utpal Anand
  • Saumya Das

DOI:

https://doi.org/10.37506/ijfmt.v16i3.18259

Keywords:

Callistemon viminalis; incision Wound model; healing potentiality; antibacterial activity

Abstract

Callistemon viminalis, often known as the stream bottlebrush, is a tropical plant in the Myrtaceae family
and is renowned for its ability to grow rapidly in riparian zones. It is exclusively found in New South Wales,
Queensland, and Western Australia. The roots of this species are entangled, which helps stabilize the soil, which
reduces the danger of erosion. This plant has antibacterial, antifungal, antioxidant, and other pharmacological
and insecticidal abilities that are also related to other medicinal properties. This research investigates the benefits,
applications, and features of several extracts obtained from components of C. viminalis (branches, flowers, fruits,
bark, and leaves). Bioactive compounds were characterized in detail by noting their chemical structures. The use
of C. viminalis in folk medicine was fully supported by the results. Collecting and compounding plant materials,
including processing, drying, and grinding, and then doing research to screen pharmaceutical effects, are all part
of making the cure. Rats had their wound healing ability tested using a method known as in vitro experimentation.
This method relies on excision wounds. The capacity of the extracted substance to close wounds when applied
as an ointment was shown to be greater than in the control. The epithelization time in the standard and treated
groups was significantly shorter than in the basic ointment base treatment group. The group treated with 5% w/w
extract ointment had greater traction intensity than the control group (1.96 gm/mm2), with a significant difference
of (1.12) gm/mm2. The tensile strength of the (3.86) gm/mm2 of the 5% w/w treated group. A substantial increase
in tensile strength was seen on the tenth day for both the extract level and the normal medicine.

Author Biographies

Avijit Mazumder

Professor and Director, Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park- II, Institutional Area, Greater Noida, Uttar Pradesh, 201306, India.

Utpal Anand

Research Scholar,  Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park- II, Institutional Area, Greater Noida, Uttar Pradesh,India.

Saumya Das

Associate Professor, Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park- II, Institutional Area, Greater Noida, Uttar Pradesh, India.

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Published

2022-07-04

How to Cite

Avijit Mazumder, Utpal Anand, & Saumya Das. (2022). Study of in Vitro Antimicrobial Activity and in Vivo Wound Healing Potentiality of Leaves of Callistemon Viminalis. Indian Journal of Forensic Medicine & Toxicology, 16(3), 96–101. https://doi.org/10.37506/ijfmt.v16i3.18259