Quantitative and Qualitative Determination of Gliotoxin and Acetaldehyde Toxins in Yeasts Isolated from some Respiratory Patients and Study of Yeast Resistance to some Antibiotics

Abstract

The concentrations (64, 128, 32, 16, 8, 4, 2, 1, 0.5, 0.25 and 0.125) mg/ml were used to calculate the lowest
inhibitory concentration of antibiotics for Candida yeast by microdilution method. The antibiotics fluconazole
and itraconazole were used to complete this experiment, which is based on the results of testing the API Candida
system by demonstrating the resistance of yeasts using several mechanisms, which serve to phenotype each
organism selected in the framework. In this test, it was found that there is resistance to the antibiotics itraconazole
and fluconazole in the types of yeasts under experiment. The toxin-producing yeasts extracted from yeasts showed
that the toxin-producing yeast species were only 27 out of 30 samples of yeast, despite the growth efficiency of all
samples. While 30 samples of yeast isolated from patients’ sputum, it was found that all samples under the current
study contain different amounts of acetaldehyde toxins with different concentrations.