Framingham Risk Score and Coronary Artery Calcium Score: How Good they Relate


  • Johanes Nugroho
  • Revi Adheriyani
  • Ardyan Wardhana
  • Makhyan Jibril Al Farabi



Framingham Risk Score; coronary calcium score; computed tomography; coronary atherosclerosis; coronary arterial disease.


Background and Aims: Screening patients for coronary arterial disease can be through risk stratification using the
Framingham Risk Score (FRS). Direct visualization of subclinical atherosclerotic lesions through coronary artery
calcium scores (CACS) can be an additional strategy. Therefore, we want to know the relationship between FRS
and CACS in asymptomatic individuals.
Method: A cross-sectional study involving 110 asymptomatic participants who undergoing health screening was
conducted in the National Hospital, Surabaya from November 2015 until January 2016. Risk stratification was
evaluated using Hard Coronary Heart Disease (10-year risk) outcomes model score and the Agatston–Janowitz’s
coronary calcium score.
Results: A significant positive correlation was observed between CACS and FRS (Spearman’s correlation coefficient
r=0.51, P<0.0001). Age and systolic blood pressure were also positively correlated with CACS. Total cholesterol
was the only parameter that showed a negative correlation with CACS. No difference in CACS value was shown
in gender and smoking status.
Conclusion: There was a strong correlation between FRS and CACS in asymptomatic individuals.

Author Biographies

Johanes Nugroho

Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Airlangga, Dr.Soetomo
GeneralHospital, Surabaya, East Java, Indonesia

Revi Adheriyani

Dr. Soetomo General Hospital, Surabaya, Indonesia

Ardyan Wardhana

Dr.Wahidin SudiroHusodo General Hospital, Mojokerto, Indonesia

Makhyan Jibril Al Farabi

Faculty of Medicine, Universitas Surabaya,Indonesia




How to Cite

Johanes Nugroho, Revi Adheriyani, Ardyan Wardhana, & Makhyan Jibril Al Farabi. (2022). Framingham Risk Score and Coronary Artery Calcium Score: How Good they Relate. Indian Journal of Forensic Medicine & Toxicology, 16(3), 214–217.