Risk Factors for Diabetic Ketoacidosis in Children with Type 1 Diabetes Mellitus: A Single-center, Cross-sectional Study in Indonesia

Authors

  • Nur Rochmah
  • Muhammad Faizi
  • Umamah
  • Anang Endaryanto
  • Soetjipto

DOI:

https://doi.org/10.37506/ijfmt.v16i4.18611

Keywords:

diabetic ketoacidosis; type 1 diabetes mellitus; risk factor; parental age; occupation

Abstract

Background: Diabetic ketoacidosis (DKA), the leading cause of mortality in childhood with diabetes mellitus
(DM). Identification of risk factors for DKA in children with type 1 DM (T1DM), can aid in reducing the incidence
of DKA.
Objective: To determine risk factors for DKA in children with T1DM.
Methods: This was a single-centre, cross-sectional study of patients aged 0–16 years diagnosed with T1DM who
were hospitalised in or visited Dr. Soetomo General Hospital in Surabaya between January 2016 and June 2021.
Data on sex, age, parental educational background, parental occupation, parental age, family history of DM and
DKA frequency were collected, and statistical analyses using the SPSS software.
Results: The risk of DKA was higher in children with working mothers (OR 9.3, 95%; CI 2.168–40.182, p = 0.003).
Significant correlation between maternal age younger than 40 years and DKA frequency (OR 1.73, 95%; CI 8.684–
3.478, p = 0.000). The highest frequency of DKA was observed in children with low parental educational level,
whereas there was no correlation between age at diagnosis and parental educational level with DKA.
Conclusion: Young maternal age and working mothers might be associated with increased frequency of DKA in
children with T1DM.

Author Biographies

  • Nur Rochmah

    Associate Professor, Department of Child Health, Faculty of Medicine, Universitas Airlangga,
    Surabaya, East Java, Indonesia,

  • Muhammad Faizi

    Associate Professor, Department of Child Health, Faculty of Medicine, Universitas Airlangga,
    Surabaya, East Java, Indonesia

  • Umamah

    Pediatrician, Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia

  • Anang Endaryanto

    Associate Professor, Department of Child Health, Faculty of Medicine, Universitas Airlangga,
    Surabaya, East Java, Indonesia

  • Soetjipto

    Professor, Department of Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia

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Published

2022-10-10

How to Cite

Risk Factors for Diabetic Ketoacidosis in Children with Type 1 Diabetes Mellitus: A Single-center, Cross-sectional Study in Indonesia. (2022). Indian Journal of Forensic Medicine & Toxicology, 16(4), 344-348. https://doi.org/10.37506/ijfmt.v16i4.18611