A Group of Iraqi Patients with type II Diabetes Mellitus have a Correlation between HbA1c, lipids, and Thyroid Hormone
DOI:
https://doi.org/10.37506/ijfmt.v17i1.18898Keywords:
Correlation, HbA1c, thyroid hormones, and cholesterol and triglyceridesAbstract
Background: The objectives of this study were to: (1) find out the levels of thyroid hormones, lipid profile, and
glycosylated hemoglobin (HbA1c) in diabetic patients type II; and (2) examine the relationship between thyroid
hormones and HbA1c, as well as distinctive sorts of lipids and HbA1c in the patient groups.
Materials and Methods: A retrospective chart review study for the group of patient’s vs control was carried
out at Al-Yarmouk Teaching Hospital in Baghdad Al-Karkh, Iraq. From December 2020 to February 2022, 100
male and female patients with type II diabetes mellitus and 100 non- diabetic males and females as controls were
included, respectively, in this study. The biochemical laboratory tests were obtained from a laboratory database
of the hospital. Statistical analysis was performed using SPSS version 21 to estimate the P-value from the T-test of
independent groups.
Results: For the patient groups compared with the control groups, there was an increase in the mean levels of both
HbA1c (7.84%) and TSH (7.65 μlU/ml), while T4 (10.31 μg/dl) and T3 (1.44 ng/ml) were normal. It also increased
mean levels of triglycerides (191.46 mg/dl) and normal total cholesterol (185.94 mg/dl). The results of the patient
groups showed an insignificant correlation between HbA1c and TSH (P = 0.96844) and a significant correlation
between HbA1c with T4 and T3 (P = 0.00323) and (P = 0.00001) respectively. Significant and positive relationship
between HbA1c and total cholesterol and triglycerides (P = 0.00001), (P = 0.00001) respectively.
Conclusion: Increased blood glucose did not cause the anterior pituitary gland to enhance TSH production,
although there was a clear link between increased glycemic index and the rate of thyroxin secretion. Furthermore,
there is a link between blood glucose and several lipid markers, according to the findings.
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