Haematological Profile in Chronic Liver Disease Patients in Geriatric Population: An Observational Study
Keywords:Chronic liver disease, Haematological profile, Geriatric
Background: The incidence of chronic liver disease is increasing worldwide. Common causes of chronic liver disease include alcohol, chronic hepatitis B and C and non-alcoholic fatty liver disease (NAFLD). Abnormalities in hematological parameters are common in patients with cirrhosis. There is paucity of data in geriatric population with chronic liver diseases.
Methods: A pre-structured performa was prepared to collect the demographic data that included Age, Gender, Occupation, Area of Residence, History of present illness (duration of illness, bleeding tendencies, abdominal distension, jaundice, oliguria). Peripheral blood smears were assessed for Anisopoikilocytosis, nucleated RBCs and morphological type of anaemia; Hypersegmented neutrophils, toxic granulation, relative lymphocytosis and immature cells/ blasts and platelet number and morphology.
Conclusion: The study categorically showed male preponderance in patients with Chronic Liver disease. Anaemia was prevalent in 89% of study population with major blood picture being normocytic normochromic anaemia. Mild to moderate thrombocytopenia was seen in 17% and leucopenia was seen in 32% of the patients.
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