Artificial Intelligence and its Role in Forensic Karyotyping: A Systematic Review


  • Sachin Kumar Tripathi
  • Khyati Rao
  • Rajiv Ratan Singh
  • Pradeep kumar Yadav



Artificial Intelligence (AI), Criminal Investigations, Forensic Karyotyping, Genetic Abnormalities, Genetic Profiles, Labelled Datasets, etc.


Introduction: One of the most important aspects of forensic investigations and genetic research is forensic
karyotyping, which involves analyzing a person’s chromosomes to find genetic anomalies and establish
identification. The development of artificial intelligence (AI) technology offers a chance to improve and automate the forensic karyotyping procedure. This study examines the possible advantages and difficulties of artificial intelligence (AI) in forensic karyotyping. In forensic science, forensic karyotyping is essential for providing an accurate interpretation of genetic data for use in legal and investigative processes. It can offer  useful details regarding genetic problems, such as chromosomal abnormalities or mutations, which can help with personal identification, paternity determination, or supplying proof in criminal investigations.
Aim: To give a general review of how artificial intelligence is used in forensic karyotyping, evaluate its possible advantages, and address any relevant issues. By being aware of Artificial Intelligence’s promise and limitations in this field, we may set the stage for its efficient integration into forensic practitioner.
Methods: A database search we did to start the inquiry turned up 582 documents. There were 216 unique records left after duplicates were eliminated. 232 items were subsequently eliminated as a result of download problems. A final sample of 31 research was chosen from the 134 full-text papers that were evaluated (n=134), with 103 being eliminated owing to quality issues.
Result: The use of artificial intelligence (AI) in forensic karyotyping has several advantages, including automated chromosomal analysis, quicker abnormality discovery, and increased uniformity. For a successful application, challenges such as a lack of labelled datasets and ethical issues must be resolved.
Concussion: By increasing productivity, precision, and uniformity, artificial intelligence has the potential to
transform forensic karyotyping. While there are obstacles, continued study and cooperation amongst several fields might help you get through them. The ethical and appropriate use of AI in forensic karyotyping will improve forensic investigations, boost genetic research, and expand the use of genetics in the legal system.

Author Biographies

  • Sachin Kumar Tripathi

    Scientific Assistant, Toxicology Department of Forensic Medicine & Toxicology, King George’s Medical
    University, Lucknow, Uttar Pradesh

  • Khyati Rao

    Research Student University of Lucknow, Lucknow Uttar PradeshIndia,

  • Rajiv Ratan Singh

    Professor (Jr), Department of Emergency Medicine, Dr.RML Institute of Medical Sciences
    Lucknow, India, Lucknow, India

  • Pradeep kumar Yadav

    Assistant Professor, Department of Forensic Medicine and Toxicology,Dr. Ram Manohar Lohia Institute Lucknow




How to Cite

Artificial Intelligence and its Role in Forensic Karyotyping: A Systematic Review. (2024). Indian Journal of Forensic Medicine & Toxicology, 18(1), 114-118.