Tramadol dependence and withdrawal syndrome: A Case report
DOI:
https://doi.org/10.37506/vhs8dv37Keywords:
Tramadol, Drug withdrawal, Seizure, Drug abuse, Drug dependenceAbstract
Tramadol is a synthetic analgesic that appears to have two mechanisms of action: a reuptake inhibition of serotonin and noradrenaline and a weak μ-opioid receptor agonism. Even though its potential for abuse is well reported, the drug is readily available off on the market and is not regarded as a controlled substance in many nations, in contrast to the majority of other opioids. The patient in this case report developed severe tramadol dependence after taking large doses of the drug to treat his musculoskeletal pain. We suggest that It should be made a controlled substance at the administrative levels due to the possibility of dependence and severe withdrawal symptoms.
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