Thiophene-Cyclic and Sulfazane Derivatives (Preparation, Spectral Analysis, the Behavior in Organic Solvents, Microbial Testing)

Authors

  • Jalal Hasan Mohammed1, Alaa Jawad Kadhim2, Nagham Mahmood Aljamali3

DOI:

https://doi.org/10.37506/ijfmt.v14i2.3166

Keywords:

Microbial ,Sulphazane, Aldol, chalcone ,thiophene ,heterocyclic, phenylene diamine, coupling,Azo,new reaction of diazonium, sulfide- azo ,(-S-N=N-), seven membered ,five membered

Abstract

The thiophene core is the most broadly applied constructing blocks to the production of many biomolecules ,pharmaceutical drugs ,vitamins ,also in industrial compounds, in dyes compounds because of its high stability in environment. Thiophene derivatives were synthesized in present study from chalcone compound as a starting material from aldol reaction in first step, followed by cyclization reactions by using various conditions, and this paper involved new reaction for diazonium salts to producing (Sulfide- azo) compounds in same bond for the first time that we termed (Sulfazane) as a first and Novel preparation to this new type of compounds.,the synthesized derivatives were confirmed through numerous spectral techniques (FT.IR ,H.NMR ,C.NMR), other physic-chemical data for synthesized thiophene derivatives ,besides to studying of behavior of compounds in organic solvents and screening tests for efficiency of thiophene derivatives against microbes

Author Biography

  • Jalal Hasan Mohammed1, Alaa Jawad Kadhim2, Nagham Mahmood Aljamali3

    1Lecturer, Department of Pharmaceutical Chemistry, College of Pharmacy, Karbala University, Iraq, 2Lecturer, Department of Chemistry, College of Education for Pure Sciences, Karbala University, Iraq, 3Assist. Professor ,Department of Chemistry, Iraq

Downloads

Published

2020-04-29

Issue

Vol. 14 No. 2 (2020): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

 

  1. The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
  2. The journal allows the author(s) to hold the copyright without restrictions.
  3. The journal allows the author(s) to retain publishing rights without restrictions

How to Cite

Thiophene-Cyclic and Sulfazane Derivatives (Preparation, Spectral Analysis, the Behavior in Organic Solvents, Microbial Testing) . (2020). Indian Journal of Forensic Medicine & Toxicology, 14(2), 1662-1669. https://doi.org/10.37506/ijfmt.v14i2.3166