Role of C-reactive Protein, Total Leukocyte count and Erythrocyte Sedimentation Rate as a Diagnostic and Prognostic Indicator in Maxillofacial Infections
Keywords:Serum markers, C-reactive protein, maxillofacial infection, odontogenic, TLC
Purpose: The aim of this study was to evaluate the role of C-reactive protein (CRP), Total Leukocyte Count
(TLC) and Erythrocyte Sedimentation Rate (ESR) levels as diagnostic and prognostic indicators in patients
diagnosed with maxillofacial odontogenic infections.
Materials and Methods: A prospective study was done among 30 patients with maxillofacial odontogenic
infections. Blood samples were collected at 3 intervals to detect the level of the study parameters followed
by incision and drainage for all the patients under Local anesthesia.
Results: The mean CRP, TLC and ESR levels gradually reduced on 5th post-operative day as compared to
day 1 and 3 suggestive of resolution of the infectious state.
Conclusion: We conclude that CRP is required only in selective cases of maxillofacial infection where
monitoring under intensive care will be required, else TLC alone is sufficient to indicate the presence of
infection along with adequate medical and surgical care.