Bacteriology and Antibiotic Sensitivity Pattern of Uropathogens in Patients with Catheter Associated Urinary Tract Infections in a Tertiary Care Hospital, Bhubaneswar, Odisha

Abstract

Background: Hospital acquired infections (HAI) serves as a significant public health problem in developing

as well as in developed country. The incidence of HAIs in ICU is rising, largely because of increasing use of

invasive procedures. About 25% of hospitalized patients undergo urinary catheterization hence it enhances

the chances of Catheter Associated Urinary Tract Infections (CAUTI) which is difficult to cure.

The present study is designed with the aim to determine the bacterial pathogens causing Urinary tract

infections (UTIs) in patients with indwelling urinary catheter and to study their antibiotic susceptibility

pattern.

Methodology: This was a Cross-Sectional, hospital-based study carried out from August to September 2018

in a tertiary care hospital in Eastern India. A convenient sample size of 50 Catheterized patients admitted

to the hospital from whom urine samples were collected. Fifty urine samples were also collected from non

catheterized patients as control group. Informed written consent was taken from patients before collecting

the urine sample. Data was entered and analyzed on Statistical Package of Social Sciences (SPSS) Version

1. Mean and Standard deviation was calculated for quantitative data and proportions were calculated for

qualitative data.

Results: The age of the patients ranged from 15 to 90 years with a mean of 50.49 years. Majority (62%)

were in 46-75 years age group and were males (68%). The rate of developing UTI was more with increase

in duration of catheterization and it was 86% with 8-14 days of catheterization. Among catheterized patients

Escherichia coli was found to be the most frequently isolated pathogen 23(36.5%) followed by Klebsiella

pneumoniae 12 (19%) and Enterococcus species 8(12.7%). Among the 31 positive samples, 10 samples

showed growth of 2 organisms and 6 samples showed growth of 3 organisms.

Conclusion: Reduction of Hospital acquired infections and antibiotic resistance is both a challenge and

goal of all health care centers around the globe. To lower our economic burden and improve the healthcare

standards of the catheterized patient admitted to the hospital we have to broaden our knowledge regarding

safe use of indwelling urinary devices.