Risk of Malignancy Index (RMI-2) in the Evaluation of Adenexal Masses

Abstract

The present prospective study, conducted in the department of Obstetrics and Gynaecology and department

of Biochemistry, Government Medical College and Rajindra Hospital,Patiala . Fifty patients after taking

a detailed history and examination underwent various investigations including CA-125 levels and

ultrasonography. RMI-2 was calculated for each patient preoperatively and later compared with respective

histopathological examination. The present study demonstrated that RMI-2 (at a cut-off value of 200) is a

screening method with high sensitivity and specificity in predicting benign or malignant nature of adenexal

masses. It is a simple, easy and useful method to apply in a tertiary care hospital. Our study reconfirms

accuracy of RMI in diagnosing adenexal masses with high risk of malignancy. Small sample size, more

number of pre-menopausal and more number of benign ovarian masses were some of the limitations of

present study.