Evaluation of Serum Oxytocin Hormone Level in Children with Autism

Abstract

Background: Autism spectrum disorder (ASD) is a gathering of complex neuro-improvement issue
portrayed by repetitive and characteristic patterns of behavior and difficulties with social correspondence
and cooperation.
Aim: to study oxytocin levels in the serum of children with autism and its relation with disorder..
Patients and Methods: Across-section study was carried out at Pediatric Hospital- Kirkuk-Iraq in a period
between the 10th of Jan 2019 30th July 2019. 55 children with autism and 25 healthy children, with the
same age group, were subjected to this study. Biochemical tests were done for estimation of serum Oxytocin
hormone levels in children with autism and comparing them with serum OT hormone levels in control
group.
Results: The results showed that there was a significant (P< 0.05) decrease in the levels of serum Oxytocin
hormone in children with autism which declined to 69.67 ± 10.122 Pg/ml as mean values among children
with autism when compared with same parameters in control children which was 108.44 ± 4.33 Pg/ml.
Conclusion: It was concluded that children with autism disorder have lower serum level of oxytocin
hormone than normal healthy children.