A Systematic Review on Effectiveness of Botulinum Toxin in the Treatment of Frey’s Syndome

Abstract

Background: The treatment of Frey’s syndrome by using Botulinum toxin is both non-invasive, comparatively
more long lasting and has a better prognosis compared to the other available treatment options to treat Frey’s
syndrome.
Aim: - The aim of the study is to undertake a systematic review and understand whether Botulinum Toxin
is a feasible treatment choice for Frey’s syndrome. .
Methodology:- The literature review was done using PubMed , Wiley online, science direct, CINALH,
Cochrane library, gray literature, Prospero, OSF, Scopus and New England Journal of Medicine. The
keywords were “Frey’s syndrome” and “Botulinum toxin”. A total of 1306 records were screened after
quantitative synthesis four articles were finalized. Meta analysis was not done to be heterogeneity in the
article included for final review.
Result: - Four studies were included in our systematic reviews which included. The studies performed in
different countries to prove the role of Botulinum toxin for Frey’s syndrome and suggest that is Botulinum
Toxin is a safe and good treatment option for Frey’s syndrome.
Conclusion: Treating the Frey’s syndrome with good prognosis is always a challenging task to the dentist.
Here the included studies have shown positive results for treatment of Hyperhidrosis or Frey’s syndrome
with Botulinum Toxin injections.