Effectiveness of Deep Brain Stimulation in Parkinsonism

Abstract

Introduction: Deep brain stimulation (DBS) is a neurosurgical procedure indicated for patients with advanced Parkinson’s disease (PD).This study aimed to investigate the relative efficacy and safety of DBS when medical therapy is ineffective in advanced PD. Material and Method: 50 patients whom were on medical treatment for long and started to have side effects of the drugs were the part of the study to find the improvement in the status in terms of tremors, dyskinesia and rigidity. Results: Preoperatively and postoperatively comparison in the improvement was done which revealed, improvement was 75%, 61.5% and 58 % respectively in tremors, rigidity and dyskinesia. There was statically significantly improvement rigidity, tremor and the dyskinesia, the patients needed smaller doses of the medications and showed less signs of distress. Conclusion: Our results clearly suggested that with Deep Brain Stimulation patients showed significant improvement with decreased dose of medication.