Prevalence of MRSA and its Antibiotic Susceptibility Pattern in a Tertiary Care Center,Karimnagar

Abstract

Background & Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) is a well-recognized
public health problem throughout the world.This study was aimed to isolate the Staphylococcus aureus from
various clinical specimens, and to study the prevalence of methicillin resistance among Staphylococcus
aureus and to evaluate phenotypic and genotypic methods in detection of MRSA and to determine its
Aantibiotic susceptibility pattern in MSSA and MRSA isolates. The study was undertaken during November
2018to October 2019.various clinical samples received from the surgical and medical departments are
included in the study.
Methods:Total 218 staphylococcus aureus strains were isolated from various clinical samples S. aureus was
identified by characteristic growth on blood agar, MacConkey agar, Gram staining and various biochemical
tests, e.g. catalase test, free and bound coagulase test, and anaerobic mannitol fermentation1. Among them
48(22.01%) were MRSA positive 170(77.9%) were MSSA
Conclusion: Early identification of MRSA is an important step toward timely implementation of appropriate
treatment. The prevalence of resistance is bound to increase with increased irrational use of antibiotics.
Robust antimicrobial stewardship and strengthened infection control measures are required to prevent
spread and reduce emergence of resistance.