Study on Association between Vitamin D and Essential Hypertension at a Tertiary Care Centre in Udaipur
Keywords:Essential Hypertension, OPD (out Patient Department), vitamin D level, vitamin D receptor
Introduction: Vitamin-D has very important role in calcium metabolism and optimum bone health.
Vitamin-D is derived from endogenous UVB (Ultraviolet-B) which induces vitamin D synthesis in the skin.
Currently very high prevalence of vitamin D deficiency in India can be attributed to the lifestyle changes and
low sunlight exposure. Identification of the vitamin-D receptor (VDR) in almost every human cells, suggest
a role in extra skeletal diseases. Various studies have shown that vitamin D deficiency is an independent risk
factor for essential hypertension.
Aim: To evaluate the association between vitamin D and essential hypertension among people coming for
out patient department at a tertiary care centre of Udaipur.
Materials and Methods: Study was carried out as a cross sectional study at a tertiary care hospital of
Udaipur. Participants (259) were both males and females (134 males and 125 females), between the age
group of 20-60 years attending the OPD clinic of our tertiary care hospital.
Statistical Analysis: Appropriate Statistical test was done using latest version of SPSS.
Results: It is found that severe vitamin D deficiency is highly prevalent in people with hypertension as
compare to people without hypertension (P value <0.001).
Conclusion: Since India is a tropical country, it was assumed that vitamin D deficiency and its ill effects
are less common. But it is found that, vitamin D deficiency is highly prevalent in people with hypertension
at Udaipur, attributed to the need of early vitamin D supplementation. Therefore, to reduce cardio-vascular
events early identification of vitamin D deficiency and appropriate vitamin D supplement may be of very
important in population with high prevalence.
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