Macrovascular and Microvascular Complications in Newly Diagnosed Type 2 Diabetes Mellitus
Keywords:Type 2 Diabetes mellitus, microvascular, macrovascular, HbA1c, CAD
Background and Objectives: India is claimed to be the diabetes capital of the world. Many studies had
proven that persistent hyperglycemia and associated metabolic syndrome features like hypertension,
dyslipidemia and obesity contribute to the development of vascular complications.
The present study aims to study the prevalence and clinical profile of microvascular and macrovascular
complications in newly diagnosed type 2 diabetes mellitus patients.
Methods: The study is a clinical, prospective and observational study of 100 newly detected type 2 diabetics
attending medicine department outpatient/ inpatient, SGRRIMHS hospital, dehradun, form the subject for
the study August 2018 to July 2020 (24 months) who matched the inclusion criteria.
Results: In this, 62 were males and 38 were females and the mean age was 54.05±13.24 years. 44% were
detected when they presented with multiple complications due to diabetes. Common complications which
they presented were coronary artery disease (15%), infection (12%), stroke (6%), ulcers (4%), neuropathy
(4%) and diabetic ketoacidosis (1%). The prevalence of macrovascular complications CAD, CVD and
PAD was 26.0%, 8.0% and 11.0% respectively and microvascular complications retinopathy, nephropathy
and neuropathy was 20.0%, 34.0% and 16.0% respectively.High incidence of complications especially
microvascular and CAD occur with HbA1c of range >6.5. The correlation coefficient of FBS and PPBS in
relation to HbA1c was 0.56 and 0.57 respectively.
Conclusion: Smoking, increased BMI and waist circumference is associated with increased prevalence
of diabetes.There is high prevalence of coronary artery disease, retinopathy and nephropathy at diagnosis.
HbA1c levels predict the prevalence of complications.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.