Gallbladder Perforation During Elective Laparoscopic Cholecystectomy Incidence, Risk Factors and Outcomes
Keywords:Alanine transaminase; gallbladder perforation; laparoscopic cholecystectomy
Objective: The goal of this study was to discover the risk factors for perforation of the gallbladder during
laparoscopic cholecystectomy, as well as the outcomes.
Methods: All patients who had an elective cholecystectomy at our department had their videotapes reviewed
retrospectively, and the patients were separated into two groups based on whether or not they had GP. The
potential risk factors as well as the early results were investigated.
Results: 664 patients were totally examined [524 (78.9%) females, 49.7±13.4 years old] were observed, and
GP (Gallbladder Perforation) occurred in 240 (36.1%) of them, usually during dissecting the gallbladder
from its bed (n=197, 82.1%). In 177 (73.8%) of the cases, the GP was not documented in the surgery
notes. There was no significant risk factor for GP among the studied parameters, with the exception of a
preoperatively high alanine transaminase level (p=0.005), which had 14.2 % sensitivity and 7.4 % specificity
in predicting GP. The two groups had comparable results; however, the GP group had a longer operation time
(35.4±17.5 vs 41.4±18.7 min, p=0.000) and a higher rate of drain usage (25 % vs 45.8%, p=0.000).
Conclusion: According to the current study, GP occurs in 36.1 % of patients who have a laparoscopic
elective cholecystectomy; however, it is not always reported. We were unable to identify any reliable risk
factors that enhance the likelihood of GP. The use of GP lengthens the surgery and increases the likelihood
of drain usage; nevertheless, the other results were found to be equivalent in patients with and without GP.
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