Adherence to multidose Hepatitis B vaccination in a Tertiary Care Centre: A Retrospective Cohort Study
Keywords:Hepatitis B Virus (HBV), Vaccination, Health care workers (HCW), Hepato-cellular Carcinoma (HCC)
Background: Globally out of 200 crore population who are getting exposed to the hepatitis B virus (HBV),
about 350 million are chronically carrying it resulting in 0.5 to 1.2 million deaths each year . These mortalities
are due to chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Horizontal transmission in early
childhood and parental transmission at any age are the important routes of transmission. This study was
conducted with following objectives.
(a) To assess the prevalence of adherence to Hepatitis vaccination.
(b) To associate this adherence with demographic factors.
Methodology: After receiving approval from the Institutional Ethics Committee a record based retrospective
cohort study was conducted at Gastroenterology and Hepatology OPD of IMS and SUM Hospital,
Bhubaneswar. Data regarding all the patients who have received First dose of Hepatitis Vaccine from January
2019 to December 2019 were followed up till June 2020 to find out how many of them have revisited to
obtain second dose as well as third dose of vaccine. Their demographic characteristics collected from the
immunisation register. Data was entered and analysed using SPSS vs 21 using appropriate statistics.
Results and conclusion: Total 1134 subjects have received the first dose of Hepatitis B vaccine. Mean
age of the participants is 36±15yrs. First dose taken by 453(39.9%) people, 324(28.6%) had completed the
schedule by taking the final dose of vaccine. Hardly one third of the patients adheres to the schedule and
completes it. Inadequate vaccination makes the patients vulnerable to risks of Hepatitis B and its morbidities.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.