Role of Radiology in Mucormycosis: Recent Update

Authors

  • Kushpreet Kaur
  • Sandeep Singh
  • Harsimrat Singh
  • Mandeep Kour

DOI:

https://doi.org/10.37506/ijphrd.v13i3.18187

Keywords:

Rhinocerebral Mucormycosis, Imaging Findings, MRI, Neuroradiology

Abstract

The purpose of this study was to describe common radiographic patterns that may be useful in predicting the diagnosis
of rhinocerebral mucormycosis. Methods: We retrospectively evaluated the imaging and clinical data of four males and
one female, 3 to 72 years old, with rhinocerebral mucormycosis. Results: All the patients presented with sinusitis and
ophthalmological symptoms. Most of the patients (80%) had isointense lesions relative to brain in T1-weighted images.
The signal intensity in T2-weighted images was more variable, with only one (20%) patient showing hyperintensity. A
pattern of anatomic involvement affecting the nasal cavity, maxillary sinus, orbit, and ethmoid cells was consistently
observed in all five patients (100%). Our series demonstrated a mortality rate of 60%. Conclusion: Progressive and rapid
involvement of the cavernous sinus, vascular structures and intracranial contents is the usual evolution of rhinocerebral
mucormycosis. In the context of immunosupression, a pattern of nasal cavity, maxillary sinus, ethmoid cells, and orbit
inflammatory lesions should prompt the diagnosis of mucormycosis. Multiplanar magnetic resonance imaging shows
anatomic involvement, helping in surgery planning. However, the prognosis is grave despite radical surgery and
antifungals.

Author Biographies

Kushpreet Kaur

Post graduate, Department of Radiology, Index medical College, Indore, M.P

Sandeep Singh

Demonstrator, Department of Pathology, GMC khandwa, M.P.

Harsimrat Singh

Senior Resident, Department of Otolaryngology, AIMSR

Mandeep Kour

Senior Resident, Department of Otolaryngology, AIMSR

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Published

2022-06-24

How to Cite

Kushpreet Kaur, Sandeep Singh, Harsimrat Singh, & Mandeep Kour. (2022). Role of Radiology in Mucormycosis: Recent Update. Indian Journal of Public Health Research & Development, 13(3), 148–150. https://doi.org/10.37506/ijphrd.v13i3.18187