Ophthalmic Manifestations in Blood Dyscrasias - An Observational Study
Keywords:Anemia, Blood dyscrasias, Retinal Veinous Tortuosity, Sub - conjunctival bleeding
Aim: The present study was conducted to study the spectrum of ophthalmic manifestations in blood dyscrasias and to
assess the prevalence of ocular manifestations between acute and chronic blood malignancies.
Material and Methods: The Present observational study was conducted on a total of 200 patients diagnosed with blood
dyscrasias at the Department of Ophthalmology, tertiary care hospital, Bhuj, during the study period of 2 years. Detailed
history and examination were conducted, and findings were noted. All relevant haematological investigations were also
Results: Out of 200 patients, anemia was the most common diagnosis observed in 70 (35%) cases, followed by sickle cell
anemia 54 (27%). Out of 70 patients with anemia, the majority of cases, i.e. 33, had iron deficiency anemia followed by
13 and 5 cases with megaloblastic and aplastic anemia, respectively. Retinal Veinous Tortuosity was the most common
finding in Thalassemia. In contrast, Veinous Fullness and Tortuosity and sub - conjunctival bleeding were the most
common finding in patients with leukemia and coagulation disorders, respectively.
Conclusion: The ocular changes of blood dyscrasias are not uncommon as is proved by various clinical and pathological
studies. These changes in the eye are due to the hemorrhagic effect of the blood disorders or due to the infiltration of the
ocular tissues by malignant cells. Ophthalmic manifestations are commonly observed in patients with blood dyscrasia.
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Copyright (c) 2022 Bhavna Dhanji Gagal, Atul A. Modesara
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