Correlation of D-Dimer Level with Severity of Pneumonia, Hospital Stay and Mortality in Case of Covid-19 Infection: A Retrospective Study an a Tertiary Care Hospital.

Authors

  • Rajashree Pradhan
  • Sajeeb Mondal
  • Somsubhra Chattopadhyay
  • Sharmistha Debnath

DOI:

https://doi.org/10.37506/ijphrd.v14i4.18588

Keywords:

COVID-19, D-dimer , pneumonia, hospital mortality.

Abstract

Introduction: Worldwide there was a pandemic of novel corona virus infection in which one of the major concern was the
risk of thrombosis and the mortality associated with it.
Aim: In this study our aim was to observe the changes in D-dimer levels during disease progression and its correlations
with severity of Pneumonia, duration of hospital stay and mortality of COVID-19 patients.
Materials & Methods: In this study we reported the clinical, radiological and pathological laboratory results of 432 cases
of confirmed COVID-19 infection. In these patients their clinical presentation, concentration of D-dimer, coagulation
parameters, CBC, severity of Pneumonia on HRCT, hospital stay and higher mortality were retrospectively analyzed.
Result: All the statistical variables were expressed in % and compared withx2 test. Out of the 432 cases in 45 cases (10.41%)
the D-dimer values were >2.4μg/ml and in 15 cases the value were very high (3.47%). When correlated these patients
found to have severe degree of pneumonia, longer hospital stay and higher mortality rate in comparison to patients with
D-dimer level of <2.4 μg/ml.
Conclusion: D-dimer level could be used as an early marker for the clinical classification, risk stratification and improved
management of COVID-19 patients.

Author Biographies

Rajashree Pradhan

Associate Professor, Department of Pathology, College of Medicine & Sagore Dutta Hospital, Kamarhati, Kolkata, West Bengal.

Sajeeb Mondal

Associate Professor, Department of Pathology, Rampurhat Government Medical College & Hospital, Birbhum, West Bengal.

Somsubhra Chattopadhyay

Associate Professor, Department of Psychiatry, College of Medicine & Sagore Dutta Hospital, Kamarhati, Kolkata, West Bengal.

Sharmistha Debnath

Associate Professor, Department of Onco, Pathology, Medical College & Hospital, Kolkata, West Bengal.

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Published

2022-10-10

How to Cite

Rajashree Pradhan, Sajeeb Mondal, Somsubhra Chattopadhyay, & Sharmistha Debnath. (2022). Correlation of D-Dimer Level with Severity of Pneumonia, Hospital Stay and Mortality in Case of Covid-19 Infection: A Retrospective Study an a Tertiary Care Hospital. Indian Journal of Public Health Research & Development, 13(4), 188–193. https://doi.org/10.37506/ijphrd.v14i4.18588