Is there an Association between the ABO Blood type and Bleeding or Clotting Times?

Abstract

Introduction: Evaluating blood type, bleeding time (BT), and clotting time (CT) are essential before surgery. Blood
type reveals personality. Multiple studies link ABO blood types to digestive (GI) disorders, urinary tract infections
(UTIs), cardiovascular diseases (CVD), diabetes, thrombosis, and epistaxis. BT and CT differ among blood types.
This study investigated the relationship between blood types and BT and CT.
Aims and Objectives: To investigate the connection between BT and CT and Blood Groups in medical students
and identify gender differences in these parameters.
Materials and Methods: This cross-sectional research was carried out between September 2021 and May 2022 on
250 healthy first-phase MBBS students (17–20 years old) of both sexes (batch 2020–2021 & 2021-22) at GMC Jammu’s
haematology laboratory. The blood group was determined using a standard antiserum Agglutination test—CT
using Wright’s Capillary tube technique and BT using Duke’s filter paper technique. Based on the methodology
above, we classify regular BT and CT as 2 to 6 minutes and 3 to 8 minutes, respectively. BT and CT levels were
examined for each blood type. The blood group distribution was reported as a percentage, the relationship between
BT or CT and blood groups was analysed using Chi-square analysis, and the gender differences between these
parameters were analysed using an unpaired t-test in SPSS 26.0.
Results: In our investigation, the distribution of ABO blood groups was determined to be: 39.6% B > 34% O >
21.2% A > 5.2% AB. Chi-square analysis revealed a non-significant ABO blood group correlation with BT (p=0.938)
and CT (p=0.652). Comparing blood types with BT and CT, the AB and B blood groups had higher mean BT
and CT values among the study participants. The blood type influenced BT/CT. Screening and prevention must
commence before the onset of bleeding disorders.

Conclusion: The most prevalent blood group among medical students was B, whereas AB was the least prevalent.
Blood types AB and B have greater levels of BT and CT. Neither BT nor CT were significantly associated with
blood type. BT and CT values were found to be greater in females