A Cross Sectional Study of Antimicrobial Resistance in Medical College Affiliated Tertiary Health Care Hospital

Abstract

Background and Objectives: The study conducted involves reviewing the current scenario of antimicrobial
resistance in the community by obtaining collected data from patients suffering from ongoing infective disorders
andanalyzing their culture and sensitivity reports.
Methods: We have collected the samples from 56 patients with infective disorders such as cellulitis, wound
infection, pneumonia, cultured the samples and checked for the sensitivity of various different antibiotics using
the disc diffusion methods according to CLSI standards. We have also checked for the morphology of the organism
by routine microscopy using gram stain.
Results: We have noted that the Gram-positive Cocci infections are more prevalent in our community settings
and there was also a high level of resistance seen in both gram-negative and gram-positive organisms, towards
the standard empirical antibiotic Cefotaxime used in such patients. Hence, we had to switch to a more effective
antibiotic according to the patterns of resistance. The presence of resistance to other antibiotics was also noted.
Interpretation & Conclusion: There is an increased level of resistance towards once considered highly effective
broad-spectrum antibiotics in the community. This may be a result of inappropriate and overzealous usage of
antibiotics by patients. This may be a result of improper supervision or no strict guidelines when it comes to the
prescription of antibiotics. Hence many different strategies must be deployed in order to tackle the development
of resistance to useful antibiotics