Study of Total Intravenous Anaesthesia in laparoscopic Surgery

Abstract

Background: Total intravenous anaesthesia in laparoscopic surgery is safer than open laparotomy operations
because propofol, a sedative hypnotic agent with excellent recovery drug and having anti-emetic properties, and
new synthetic opioids (fentanyl congeners) provide excellent analgesia; hence, TIVA has become more popular in
laparoscopic surgery.
Method: 45 adult patients aged between 18 to 65 undergoing laparoscopic surgery were studied. A solution
of propofol containing different concentrations of sufentanil (1 μgm per ml and 2 μgmper ml) was infused.
Patient’s HR, SBP, DBP, MAP, and peripheral O2 saturation from the anaesthesia monitor was taken as a baseline
measurement. All the hemodynamic parameters were recorded intra-operatively at different intervals of duration.
Results: The changes in mean values of hemodynamic values were insignificant, and only significant parameters
were noted. 158.12 (± 80.9) mean value time to rescue analgesia (in minutes) Post-surgical complications are 3
(6.6%) Nausea and vomiting
Conclusion: Propofol, containing different concentrations of sufentanil, provides hemodynamic stability with
the least post-surgical complications; hence, total intravenous anaesthesia is an ideal substitute for inhalation
anaesthesia in laparoscopic surgery because inhalation anaesthesia has a higher risk of hemodynamic instability.