Infiltration of Appendix with Eosinophils in Acute Appendicitis

Abstract

Background and Aim: Despite the fact that the precise origin of acute appendicitis is unknown, luminal obstruction, nutrition, and hereditary factors are likely to be involved. The intricate evolutionary history of the appendix and the broad ranges in evolutionary rates among various animals suggest that the feature is recurrent. Keeping the above points in mind, the present study aimed to study the etiology and prevalence of eosinophilic appendicitis.
Material and Methods: The present is the prospective study done in the department of pathology in the medical college associated with a hospital. A total of 250 cases were studied for one year. Tissue specimens were included from appendectomy procedure done either as an elective or emergency procedure. For light microscopy, one slide from each block was stained with H&E to arrive at a diagnosis.
Results: The most common reason for performing appendectomies was acute appendicitis in 144 instances,
followed by peri-appendicitis in cases. A male predominance was also noted in cases of acute appendicitis and peri appendicitis. The most frequent age range to be affected in eosinophilic appendicitis cases was 10 to 20 years. Twenty individuals were diagnosed with eosinophilic appendicitis out of the 250 cases that were received. In these cases, the muscularis propria had eosinophil infiltration, and there were a few spots where there was edema dividing the muscle fibres.
Conclusion: Rare condition known as acute eosinophilic appendicitis has hazy symptoms. In order to effectively approach and manage patients, it needs to be thoroughly investigated. The mainstay for making diagnoses continues to be histopathology.