A Study on Impact of Smoking on Semen Parameters
DOI:
https://doi.org/10.37506/rcbzhp11Keywords:
Smoking, Semen parameter, Lifestyle, Male infertility.Abstract
Introduction: Infertility approximately affects 15% of couple in India, among which male factor infertility is
associated as contributing factor causing infertility in 40- 50% of cases and sole cause in 15 -20% of cases. Semen analysis is a standard investigating tool in evaluating male infertility. Lifestyle factors namely diet, obesity, smoking, alcohol, stress, play a major role in health. Among these factors smoking is inevitable, causing detrimental effects on semen parameters and associated with lower fertility rates.
Methodology: A cross sectional study was conducted among 295 male partners of women with infertility,
attending the fertility Clinic, in reproductive medicine department over 10 months. Two hundred andninety five men satisfying the inclusion and exclusion criteria were selected by simple random sampling technique. The semen parameters of the participants were analysed, entire socio-demographic profile and detailed history was obtained using structured questionnaire and confidentiality was maintained. The results were ascertained using SPSS.
Results: Among 295 participants, total 99 (33.55%) men had abnormal semen parameters. Nearly half of the
study subjects (i.e.) 148 (50%) among 295 subjects were found to be smokers. Among 99 male with abnormal
semen parameters, 60 (61%) men who had abnormal semen parameters were smokers. This study proves a strong association between smoking on male fertility (1.9 times greater risk among smokers). Significant association (x 2 = 6.492, p = 0.0108) was found between smoking, reduced semen parameters and quality.
Conclusion: Lifestyle modifications such as cessation of smoking, premarital and pre-conception health checkups, counselling, voluntary fertility testing by male partners, early detection and appropriate intervention the saves the reproductive potential. Men must be health educated for developing knowledge on ill effects of smoking, positive attitude, behavioural change and accept his responsibility for strengthening and caring his female partner amidst the societal pressures. Thus the present study substantiates more evidence to the existing literature.
References
World Health Organization. Infections, pregnancies,
and infertility: perspectives on prevention. World
Health Organization. Fertil Steril. 1987; 47 (6): 964– 8.
Ramlau-Hansen CH, Thulstrup AM, Aggerholm
AS, Jensen MS, Toft G, Bonde JP. Is smoking a risk
factor for decreased semen quality? A cross-sectional
analysis. Hum Reprod. 2007;22:188–196.
Joesbury KA, Edirisinghe WR, Phillips MR, Yovich JL.
Evidence that male smoking affects the likelihood of
a pregnancy following IVF treatment: application of
the modified cumulative embryo score. Hum Reprod.
;13(6):1506–1506
A. Hosseinzadeh Colagar , G.A. Jorsaraee and E.
TahmasbpourMarzony , 2007. Cigarette Smoking
and the Risk of Male Infertility. Pakistan Journal of
Biological Sciences.2007;(10): 3870-3874.
Hassa H, Yildirim A, Can C, Turgut M, Tanir HM,
Senses T, Sahin-Mutlu F. Effect of smoking on semen
parameters of men attending an infertility clinic. Clin
Exp Obstet Gynecol. 2006;33(1):19-22. PMID: 16761532.
Kovac JR, Khanna A, Lipshultz LI. The effects of
cigarette smoking on male fertility. Postgrad Med.
Apr;127(3):338-41.
Vine MF, Margolin BH, Morrison HI, Hulka BS.
Cigarette smoking and sperm density: a meta-analysis.
Fertil Steril. 1994 Jan;61(1):35-43. PMID: 8293842.
Harlev A, Agarwal A, Gunes SO, Shetty A, du Plessis
SS. Smoking and Male Infertility: An Evidence-Based
Review. World J Mens Health. 2015 Dec;33(3):143-60.
Tremellen K. Oxidative stress and male infertility:
a clinical perspective. Hum Reprod Update. 2008;
:243–258.
Kao SH, Chao HT, Chen HW, Hwang TI, Liao TL, Wei
YH. Increase of oxidative stress in human sperm with
lower motility. Fertil Steril. 2008; 89:1183–1190.
Bundhun PK, Janoo G, Bhurtu A, Teeluck AR,
Soogund MZS, Pursun M, Huang F. Tobacco smoking
and semen quality in infertile males: a systematic
review and meta-analysis. BMC Public Health. 2019
Jan 8;19(1):36.
Banerjee A, Pakrashi A, Chatterjee S, Ghosh S, Dutta
SK. Semen characteristics of tobacco users in India.
Arch Androl 1993;30(1):35-40.
Chitta, Shrinivas & Tambe, Mohan &Kherde, Piyush
& Aggarwal, Sumit & Nandedkar, Prerna & Atram,
Gajanan. Effect of Cigarette Smoking on Semen Quality
Parameters in Male Partners of Infertile Couple: A
Cross Sectional Study. IOSR Journal of Dental and
Medical Sciences.2016. 15. 112-116. 10.9790/0853-
Ranganathan P, Rao KA, Thalaivarasai Balasundaram
S. Deterioration of semen quality and sperm-DNA
integrity as influenced by cigarette smoking in fertile
and infertile human male smokers—A prospective
study. J Cell Biochem. 2019;120:11784–93.
Kulaksiz, D., Toprak, T., Tokat, E. et al. Sperm
concentration and semen volume increase after
smoking cessation in infertile men. Int J Impot Res.
34, 614–619 .
Nadeem, Farkhunda; Fahim, Amin; and Bugti, Saira,
“Effects of cigarette smoking on male fertility,”
Turkish Journal of Medical Sciences. 2012. Vol. 42: No.
, Article 7, 1400 - 1405.
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