A Study on Drug Utilization in Hypertension in Medical Care Hospital

Abstract

Blood Pressure is the product of the cardiac output (CO) and Total Peripheral Resistance (TPR). Hypertension
means elevation of arterial blood pressure. Anti-Hypertensive drugs are the agents which either decreases or
normalize the elevated blood pressure.
Objective: To study the prescription pattern of anti- hypertensive agents in the General Medicine department
of Private Medical Hospital, Ahmedabad, Gujarat.
Methodology: A cross sectional observational study was carried for one month duration.
Results: During study, 100 hypertensive cases were collected. Among which 55% were males and 45% were
females who were prescribed with anti-hypertensive agents. From various anti- hypertensive drugs, six major
classes were commonly prescribed to the patients. It includes Diuretics (Ds), Calcium Channel Blockers
(CCBs), Angiotensin Receptor Blockers (ARBs), Beta Adrenergic Blockers (BABs), Alpha Adrenergic
Blockers (AABs) and Angiotensin Converting Enzyme Inhibitors (ACEIs). ARBs were prescribed in 31
prescriptions whereas; AABs were given in 4 patients only.
Conclusion: Among beta blockers, Metoprolol was the most frequently utilized anti-hypertensive drug
(31.48%) and Ramipril was the least utilized drug (1.36%). The telmisartan+amlodipine FDC was the
common prescribed in patients with indication of CVS complications.