Effectiveness of Low-Level Laser Therapy and Low Intensity Pulsed Ultrasound in Sensory Recovery in Experimentally Induced Peripheral Nerve Injury Rat Model

Authors

  • Hepsibha C R
  • Prathap Suganthirababu S
  • Lavanya Prathap
  • Mydhili Govindarasu
  • Kumaresan. A
  • Vignesh Srinivasan
  • Jagatheesan Alagesan

DOI:

https://doi.org/10.37506/w48ezp69

Keywords:

Low level laser therapy, Sensory recovery, Peripheral nerve injuries.

Abstract

Background: Peripheral nerve injuries are known to cause significant functional impairment and diminished
sensory recovery, necessitating the exploration of effective therapeutic interventions.
Purpose: The purpose of this research is to find the effectiveness of low-level laser therapy (LLLT) and low intensity
pulsed ultrasound (LIPUS) sensory recovery in an experimentally induced peripheral nerve injury rat model.
Materials and Methods: In this study, 18 adult male wistar rats which are divided into LLLT (n = 6), LIPUS (n = 6),
and control (n = 6) groups. All rats underwent a standardized procedure to induce peripheral nerve injury, while
the control group received sham procedures. Hot-Plate test and Cold-Plate Tests were conducted for pre- and
post-operative evaluation of sensory recovery at POD 7, 14, 21 days.
Results: The study’s findings revealed that LLLT exhibited significantly improved sensory recovery compared to
LIPUS and control groups on POD 14 and 21, indicating its potential as a promising non-invasive intervention for
managing peripheral nerve injuries (P <0.001).
Conclusion: The study recommends that LLLT is more effective when compared with LIPUS in promoting sensory
recovery and enhancing in a rat model of peripheral nerve injury. Positive outcomes indicate LLLT’s potential as
a promising intervention for managing peripheral nerve injuries.

Downloads

Download data is not yet available.

Author Biographies

  • Hepsibha C R

    Post graduate Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical sciences, Chennai, Tamil Nadu, India

  • Prathap Suganthirababu S

    Professor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical sciences, Chennai, Tamil Nadu, India

  • Lavanya Prathap

    Associate Professor, Department of Anatomy, Saveetha Dental College, Saveetha Institute of Medical and Technical sciences, Chennai,Tamil Nadu, India

  • Mydhili Govindarasu

    Assistant Professor, BRULAC, Saveetha Institute of Medical and Technical sciences,
    Chennai, Tamil Nadu, India

  • Kumaresan. A

    Professor,  Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical sciences, Chennai, Tamil Nadu, India,

  • Vignesh Srinivasan

    Assistant Professor, Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical sciences, Chennai, Tamil Nadu, India

  • Jagatheesan Alagesan

    Professor,  Saveetha College of Physiotherapy, Saveetha Institute of Medical and Technical sciences, Chennai, Tamil Nadu, India,

Downloads

Published

2024-01-21

How to Cite

Effectiveness of Low-Level Laser Therapy and Low Intensity Pulsed Ultrasound in Sensory Recovery in Experimentally Induced Peripheral Nerve Injury Rat Model. (2024). Indian Journal of Physiotherapy & Occupational Therapy - An International Journal, 18(5), 108-113. https://doi.org/10.37506/w48ezp69