Effectiveness of low-level Laser Therapy and Low Intensity Pulsed Ultrasound on Motor Recovery among Experimentally Induced Peripheral Nerve Injury in Wistar Rats

Abstract

Background: Damage or disease can result in peripheral nerve injury, which is a frequent clinical issue. It frequently
renders a person disabled by causing severe sensory loss and motor deficiencies along with pain, tingling, burning
and other nagging sensations. A form of ultrasound called Low-intensity pulsed ultrasound, which uses far less
energy than normal ultrasound (3 W/cm2). A biological reaction is triggered by low-level laser light having a
wavelength of 808nm and a power range of 1-1000 mW.
Purpose: The Study is to find out the effect of low-level laser therapy and low intensity pulsed ultrasound on
motor recovery among experimentally induced peripheral nerve injury in Wistar rats.
Methods: Eighteen rats were chosen in total, skin hair was removed to expose the sciatic nerve area, and the crush
injury was done by hemostatic forceps for 30 seconds, the group 1 is ultrasound, group 2 is laser and group 3 is
control group. The Step Length Ratio (SLR) was used as an outcome measure to assess motor recovery.
Result: All three groups are statistically significant (p<0.001) was analysed using one-way ANOVA during
intervention period (7th, 24th, 21st day) but LLLT & UST has shown better improvement in their functional index
than the control group.
Conclusion: According to the results, LLLT has more impact in motor recovery than LIPU also each treatment has
substantial impact on accelerating nerve regeneration and shortening the recovery time.