Exercise Tolerance And Pulmonary Function Among Middle Aged People With And Without Diabetes Mellitus.
DOI:
https://doi.org/10.37506/y0t4nb52Keywords:
Pulmonary Function Test, Type 2 diabetes mellitus, exercise tolerance, middle aged individuals.Abstract
OBJECTIVE: To assess and to compare exercise tolerance and pulmonary function among middle aged persons with type 2 Diabetes Mellitus and without.
METHODS A total of 30 patients ,15 with type 2 diabetes and 15 age matched controls without diabetes recruited from a tertiary hospital, participated in the study. Exercise tolerance and pulmonary function was assessed using six -minute walk test and spirometer respectively, for both the groups.
RESULTS: In the statistical analysis, the control group was seen to fare better in all the parameters. When analysed between groups using t test, FEV1, (t=11.350, p= <0.001) FVC (t=6.249, p= <0.001), FEV1/FVC (t=13.184, p=<0.001) and 6MWT (t=11.74100, p=<0.001) was found to be significantly different between diabetic and normal group. Analysis using chi square test showed a significant difference in lung function between diabetic and non-diabetic participants.
CONCLUSION: Middle aged non-diabetic individuals showed normal performance in exercise tolerance and pulmonary function, whereas the Diabetic population had reduced exercise tolerance and pulmonary function. This implies that middle age could be a crucial stage for early prevention of decline in pulmonary function and exercise tolerance and also to prevent future complications in type 2 diabetic patients.
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Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, Ostolaza H, Martín C. Pathophysiology of type 2 diabetes mellitus. Int J Mol Sci. 2020 Aug 30;21(17):6275.
Kumar A, Gangwar R, Ahmad Zargar A, Kumar R, Sharma A. Prevalence of diabetes in India: A review of IDF diabetes atlas 10th edition. Current diabetes reviews. 2024 Jan 1;20(1):105-14.
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018 Feb;14(2):88-98.
Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian J Ophthalmol. 2021 Nov;69(11):2932-2938.
Santrock, J. W. (2017). Life-span development.New York: McGraw-Hill Education;2017.250
Taylor KS, Heneghan CJ, Farmer AJ, Fuller AM, Adler AI, Aronson JK, Stevens RJ. All-cause and cardiovascular mortality in middle-aged people with type 2 diabetes compared with people without diabetes in a large UK primary care database. Diabetes care. 2013 Aug 1;36(8):2366-71.
Kaparianos A, Argyropoulou E, Sampsonas F, Karkoulias K, Tsiamita M, Spiropoulos K. Pulmonary complications in diabetes mellitus. Chronic respiratory disease. 2008 May;5(2):101-8.
Singh V, Nair Gb. Comparative Analysis Of Dynamic Pulmonary Function Test In Diabetics And Non Diabetics. Int J Basic Appl Physiol. 2020;9(1):67.
Donna Frownfelter, Elizabeth Dean, Marcia Stout, Rob Kruger, Joseph Anthony. Cardiovascular and Pulmonary Physical Therapy. 5th ed. USA: Elsevier Health Sciences; 2022
Hayes D, Kraman SS. The physiologic basis of spirometry. Respiratory care. 2009 Dec 1;54(12):1717-26.
Kuziemski K, Słomiński W, Jassem E. Impact of diabetes mellitus on functional exercise capacity and pulmonary functions in patients with diabetes and healthy persons. BMC Endocr Disord. 2019 Jan 3;19(1):2.
Adeniyi AF, Uloko AE, Sani-Suleiman I. Exercise capacity in type 2 diabetes patients: a preliminary investigation. African Journal of Biomedical Research. 2009;12(3):175-9..
Salih M, Mahmood HJ. The effect of a six-minute walking test on glucose levels among patients with type 2 diabetes. TMJ. 2022 June; 45(4): 6427-35.
Fang ZY, Sharman J, Prins JB, Marwick TH. Determinants of exercise capacity in patients with type 2 diabetes. Diabetes Care. 2005 Jul;28(7):1643-8.
Hsia CC, Raskin P. Lung function changes related to diabetes mellitus. Diabetes Technol Ther 2007 Jun 1;9(S1):S-73.
Fritschi C, Bronas UG, Park CG, Collins EG, Quinn L. Early declines in physical function among aging adults with type 2 diabetes. JDC2017 Feb 1;31(2):347-52.
Abdulsaid R, Sajid A, Akar TK. Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests. Iraqi Journal of Pharmaceutical Sciences (P-ISSN 1683-3597 E-ISSN 2521-3512). 2023 Sep 25;32(2):25-32
Al-Khlaiwi T, Alsabih AO, Khan A, Habib SH, Sultan M, Habib SS. Reduced pulmonary functions and respiratory muscle strength in type 2 diabetes mellitus and its association with glycemic control. Eur Rev Med Pharmacol Sci. 2021 Dec 1;25(23):7363-8.
Tesema DG, Gobena T, Ayalew A. Pulmonary function tests and their associated factors among type 2 diabetic patients at Jimma Medical Center, in 2019; comparative cross-sectional study. Int. J. Gen. Med. 2020 Apr 8:111-9.
Gangisetty SR, Devarmani SS, Nemagouda S, Warad VK, Balaganur SG, Kattimani R. Study of Pulmonary Function in Patient with Type 2 Diabetes Mellitus. Annals of AIMDR. 2018;4(2):12.
Rani RE, Ebenezer BI, Venkateswarlu M. A study on pulmonary function parameters in type 2 diabetes mellitus. National Journal of Physiology, Pharmacy and Pharmacology. 2019 Jan 1;9(1):53-7.
Tesema DG, Gobena T, Ayalew A. Pulmonary function tests and their associated factors among type 2 diabetic patients at Jimma Medical Center, in 2019; comparative cross-sectional study. Int. J. Gen. Med. 2020 Apr 8:111-9.
Niazi S, Hassan SH, Ahmed I, Ashfaq A. Effects of type two diabetes mellitus on lung function parameters. Sch J Appl Med Sci. 2013;1:482-7.
Rajput S, Parashar R, Sharma JP, Raghuwanshi P, Pakhare AP, Joshi R, Hulke S. Assessment of Pulmonary Functions and Dysfunctions in Type II Diabetes Mellitus: A Comparative Cross-Sectional Study. Cureus. 2023 Feb 16;15(2):e35081.
Gautam R. A Comparative Study of Pulmonary Functions in Patients with Type 2 Diabetes Mellitus and Normal Individuals. PIMR; 2021;9(1):59-63.
Rohling M, Pesta D, Markgraf DF, Strassburger K, Knebel B, Burkart V, Szendroedi J, Müssig K, Roden M, GDS Study Group. Metabolic determinants of impaired pulmonary function in patients with newly diagnosed type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes. 2018 Oct;126(09):584-9.
Sagun G, Gedik C, Ekiz E, Karagoz E, Takir M, Oguz A. The relation between insulin resistance and lung function: a cross - sectional study. BMC pulmonary medicine. 2015 Dec;15:1-8.
Klein OL, Krishnan JA, Glick S, Smith LJ. Systematic review of the association between lung function and Type 2 diabetes mellitus. Diabetic medicine. 2010 Sep;27(9):977-87.
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