Age-Stratified Effects of Exercise on Foot Posture, Balance and Functional Performance in Type 2 Diabetes Mellitus : Randomized Controlled Trial

Authors

  • Nishat Quddus Associate Professor, Department of Physiotherapy, Jamia Hamdard,
  • Shishir K Rastogi Ex Head, Deptt of Orthopedics, HAHC
  • Deepika Singla Assistant Professor, Department of Physiotherapy, Jamia Hamdard
  • Mohd Yoosuf Research Scholar, Department of Occupational therapy, Jamia Hamdard

DOI:

https://doi.org/10.37506/7wmvb815

Keywords:

Type 2 diabetes mellitus, exercise therapy, foot posture, balance, functional performance, aging.

Abstract

Background: Type 2 diabetes mellitus (T2DM) is associated with impairments in foot posture, balance, and functional
performance, which may be further influenced by aging. However, age-related differences in response to exercise
interventions remain insufficiently explored.
Objective: To evaluate age-stratified effects of a structured exercise program on foot posture, balance, and functional
performance in individuals with T2DM.
Methods: In this controlled, age-stratified study, 54 participants with T2DM were allocated to an exercise (n=27) or control
group (n=27) and further stratified into middle-aged (40–59 years) and older (60–80 years) subgroups. The intervention
consisted of an 8-week structured physiotherapy program. Outcomes included Foot Posture Index (FPI), static balance
(center of gravity sway on firm surface), dynamic balance (Limits of Stability), and functional performance (6-minute walk
test), assessed at baseline, 4 weeks, and 8 weeks.
Results: The exercise group demonstrated significant improvements in foot posture, balance, and functional performance
compared to controls (p < 0.05). FPI scores improved toward neutral alignment, while static and dynamic balance showed
reduced sway and enhanced stability. Functional performance improved significantly, exceeding clinically meaningful
thresholds. Age-stratified analysis revealed greater improvements in foot posture among middle-aged participants, whereas
balance and functional gains were observed across both age groups, with comparable improvements in older adults.
Conclusion: Structured exercise significantly improves foot posture, balance, and functional performance in individuals
with T2DM. While age influences the magnitude of structural adaptation, functional and balance improvements are
preserved in older adults, supporting the use of exercise interventions across age groups.

Downloads

Download data is not yet available.

Author Biographies

  • Nishat Quddus, Associate Professor, Department of Physiotherapy, Jamia Hamdard,

    Associate Professor, Department of Physiotherapy, Jamia Hamdard

  • Shishir K Rastogi, Ex Head, Deptt of Orthopedics, HAHC

    Ex Head, Deptt of Orthopedics, HAHC

  • Deepika Singla, Assistant Professor, Department of Physiotherapy, Jamia Hamdard

    Assistant Professor, Department of Physiotherapy, Jamia Hamdard

  • Mohd Yoosuf, Research Scholar, Department of Occupational therapy, Jamia Hamdard

    Research Scholar, Department of Occupational therapy, Jamia Hamdard

References

Magliano DJ, Boyko EJ, IDF Diabetes Atlas 10th

edition scientific committee. IDF DIABETES ATLAS

[Internet]. 10th ed. Brussels: International Diabetes

Federation; 2021 [cited 2026 Mar 19]. (IDF Diabetes

Atlas). Available from: http://www.ncbi.nlm.nih.

gov/books/NBK581934/ PubMed PMID: 35914061.

Brownlee M. Biochemistry and molecular cell biology

of diabetic complications. Nature. 2001;414(6865):

–20. doi:10.1038/414813a

Zimny S, Schatz H, Pfohl M. The Role of Limited

Joint Mobility in Diabetic Patients With an At-Risk

Foot. Diabetes Care. 2004;27(4):942–6. doi:10.2337/

diacare.27.4.942

Allet L, Armand S, Golay A, Monnin D, De Bie RA,

De Bruin ED. Gait characteristics of diabetic patients:

a systematic review. Diabetes Metab Res Rev.

;24(3):173–91. doi:10.1002/dmrr.809

Richardson JK, Thies SB, DeMott TK, Ashton-Miller

JA. Interventions Improve Gait Regularity in Patients

with Peripheral Neuropathy While Walking on an

Irregular Surface Under Low Light. J Am Geriatr Soc.

;52(4):510–5. doi:10.1111/j.1532-5415.2004.52155.x

Cadore EL, Izquierdo M. Exercise interventions in

polypathological aging patients that coexist with

diabetes mellitus: improving functional status and

quality of life. AGE. 2015;37(3):64. doi:10.1007/s11357-

-9800-2

Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan

DW, Dempsey PC, et al. Physical Activity/Exercise

and Diabetes: A Position Statement of the American

Diabetes Association. Diabetes Care. 2016;39(11):

–79. doi:10.2337/dc16-1728

Armstrong MJ, Colberg SR, Sigal RJ. Moving

Beyond Cardio: The Value of Resistance Training,

Balance Training, and Other Forms of Exercise

in the Management of Diabetes. Diabetes Spectr.

;28(1):14–23. doi:10.2337/diaspect.28.1.14

Khurshid S, Saeed A, Kashif M, Nasreen A, Riaz H.

Effects of multisystem exercises on balance, postural

stability, mobility, walking speed, and pain in patients

with diabetic peripheral neuropathy: a randomized

controlled trial. BMC Neurosci. 2025;26(1):16.

doi:10.1186/s12868-024-00924-6

Shaffer S, Harrison A, Brown K, Brennan K. Reliability

and validity of Semmes-Weinstein Monofilament

testing in older community-dwelling adults. Journal

of Geriatric Physical Therapy. 2005 Dec 1;28(3):112-3.

Redmond AC, Crosbie J, Ouvrier RA. Development

and validation of a novel rating system for scoring

standing foot posture: The Foot Posture Index.

Clin Biomech. 2006;21(1):89–98. doi:10.1016/j.

clinbiomech.2005.08.002

Koltermann JJ, Gerber M, Beck H, Beck M. Validation

of the HUMAC balance system in comparison with

conventional force plates. Technologies. 2017 Jul

;5(3):44.

Mickle KJ, Munro BJ, Lord SR, Menz HB, Steele JR.

Foot Pain, Plantar Pressures, and Falls in Older People:

A Prospective Study. J Am Geriatr Soc. 2010;58(10):

–40. doi:10.1111/j.1532-5415.2010.03061.x

Horak FB. Postural orientation and equilibrium: what

do we need to know about neural control of balance

to prevent falls? Age Ageing. 2006;35(suppl_2):ii7–11.

doi:10.1093/ageing/afl077

Grewal GS, Schwenk M, Lee-Eng J, Parvaneh S,

Bharara M, Menzies RA, et al. Sensor-Based Interactive

Balance Training with Visual Joint Movement

Feedback for Improving Postural Stability in Diabetics

with Peripheral Neuropathy: A Randomized

Controlled Trial. Gerontology. 2015;61(6):567–74.

doi:10.1159/000371846

Akbari NJ, Naimi SS. The effect of exercise therapy

on balance in patients with diabetic peripheral

neuropathy: a systematic review. J Diabetes Metab

Disord. 2022;21(2):1861–71. doi:10.1007/s40200-022-

-1

Fried PJ, Pascual-Leone A, Bolo NR. Diabetes and

the link between neuroplasticity and glutamate in

the aging human motor cortex. Clin Neurophysiol.

;130(9):1502–10. doi:10.1016/j.clinph.2019.04.721

Fernando M, Crowther R, Lazzarini P, Sangla K,

Cunningham M, Buttner P, et al. Biomechanical

characteristics of peripheral diabetic neuropathy: A

systematic review and meta-analysis of findings from

the gait cycle, muscle activity and dynamic barefoot

plantar pressure. Clin Biomech. 2013;28(8):831–45.

doi:10.1016/j.clinbiomech.2013.08.004

Bus SA, Waaijman R, Arts M, De Haart M, Busch-

Westbroek T, Van Baal J, et al. Effect of Custom-Made

Footwear on Foot Ulcer Recurrence in Diabetes.

Diabetes Care. 2013;36(12):4109–16. doi:10.2337/dc13-

Bus SA, Maas M, De Lange A, Michels RPJ, Levi M.

Elevated plantar pressures in neuropathic diabetic

patients with claw/hammer toe deformity. J

Biomech. 2005;38(9):1918–25. doi:10.1016/j.jbiomech.

07.034

Andersen H, Nielsen S, Mogensen CE, Jakobsen

J. Muscle Strength in Type 2 Diabetes. Diabetes.

;53(6):1543–8. doi:10.2337/diabetes.53.6.1543

Ferreira JP, Sartor CD, Leal ÂMO, Sacco ICN,

Sato TO, Ribeiro IL, et al. The effect of peripheral

neuropathy on lower limb muscle strength in diabetic

individuals. Clin Biomech. 2017;43:67–73. doi:10.1016/j.

clinbiomech.2017.02.003

Churchward-Venne TA, Tieland M, Verdijk LB,

Leenders M, Dirks ML, De Groot LCPGM, et al.

There Are No Nonresponders to Resistance-Type

Exercise Training in Older Men and Women. J Am

Med Dir Assoc. 2015;16(5):400–11. doi:10.1016/j.

jamda.2015.01.071

Morrison S, Colberg SR, Mariano M, Parson HK, Vinik

AI. Balance Training Reduces Falls Risk in Older

Individuals With Type 2 Diabetes. Diabetes Care.

;33(4):748–50. doi:10.2337/dc09-1699

Lim YC, Sidarta A, Gonzalez PC, Zhang JJ, Kwong

PWH, Chua KSG. Age related alteration in EEG

evoked responses to balance perturbations on an

inclined surface. Sci Rep. 2026;16:8078. doi:10.1038/

s41598-026-39139-6

Bohannon RW, Crouch R. Minimal clinically important

difference for change in 6-minute walk test distance

of adults with pathology: a systematic review. J Eval

Clin Pract. 2017;23(2):377–81. doi:10.1111/jep.12629

PubMed PMID: 27592691.

Monteiro RL, Ferreira JSSP, Silva ÉQ, Cruvinel-Júnior

RH, Veríssimo JL, Bus SA, et al. Foot-ankle therapeutic

exercise program can improve gait speed in people

with diabetic neuropathy: a randomized controlled

trial. Sci Rep. 2022;12(1):7561. doi:10.1038/s41598-

-11745-0

Corut H, Savci S, Ozcan Kahraman B, Tanrıverdı A,

Adıyaman SC, Acar S, et al. Which field test should be

used to compare the functional exercise capacities of

patients with type 2 diabetes mellitus with and without

diabetic peripheral neuropathy? Cross-sectional

study. Endocrinol Diabetes Nutr. 2023;70(4):277–85.

doi:10.1016/j.endien.2023.02.007

Breen L, Phillips SM. Skeletal muscle protein

metabolism in the elderly: Interventions to counteract

the “anabolic resistance” of ageing. Nutr Metab.

;8(1):68. doi:10.1186/1743-7075-8-68

Kumar V, Atherton PJ, Selby A, Rankin D, Williams

J, Smith K, et al. Muscle Protein Synthetic Responses

to Exercise: Effects of Age, Volume, and Intensity.

J Gerontol A Biol Sci Med Sci. 2012;67(11):1170–7.

doi:10.1093/gerona/gls141

Downloads

Published

2026-04-18

How to Cite

Age-Stratified Effects of Exercise on Foot Posture, Balance and Functional Performance in Type 2 Diabetes Mellitus : Randomized Controlled Trial. (2026). Indian Journal of Physiotherapy and Occupational Therapy - An International Journal, 20(2), 170-180. https://doi.org/10.37506/7wmvb815