Age-Stratified Effects of Exercise on Foot Posture, Balance and Functional Performance in Type 2 Diabetes Mellitus : Randomized Controlled Trial
DOI:
https://doi.org/10.37506/7wmvb815Keywords:
Type 2 diabetes mellitus, exercise therapy, foot posture, balance, functional performance, aging.Abstract
Background: Type 2 diabetes mellitus (T2DM) is associated with impairments in foot posture, balance, and functional
performance, which may be further influenced by aging. However, age-related differences in response to exercise
interventions remain insufficiently explored.
Objective: To evaluate age-stratified effects of a structured exercise program on foot posture, balance, and functional
performance in individuals with T2DM.
Methods: In this controlled, age-stratified study, 54 participants with T2DM were allocated to an exercise (n=27) or control
group (n=27) and further stratified into middle-aged (40–59 years) and older (60–80 years) subgroups. The intervention
consisted of an 8-week structured physiotherapy program. Outcomes included Foot Posture Index (FPI), static balance
(center of gravity sway on firm surface), dynamic balance (Limits of Stability), and functional performance (6-minute walk
test), assessed at baseline, 4 weeks, and 8 weeks.
Results: The exercise group demonstrated significant improvements in foot posture, balance, and functional performance
compared to controls (p < 0.05). FPI scores improved toward neutral alignment, while static and dynamic balance showed
reduced sway and enhanced stability. Functional performance improved significantly, exceeding clinically meaningful
thresholds. Age-stratified analysis revealed greater improvements in foot posture among middle-aged participants, whereas
balance and functional gains were observed across both age groups, with comparable improvements in older adults.
Conclusion: Structured exercise significantly improves foot posture, balance, and functional performance in individuals
with T2DM. While age influences the magnitude of structural adaptation, functional and balance improvements are
preserved in older adults, supporting the use of exercise interventions across age groups.
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References
Magliano DJ, Boyko EJ, IDF Diabetes Atlas 10th
edition scientific committee. IDF DIABETES ATLAS
[Internet]. 10th ed. Brussels: International Diabetes
Federation; 2021 [cited 2026 Mar 19]. (IDF Diabetes
Atlas). Available from: http://www.ncbi.nlm.nih.
gov/books/NBK581934/ PubMed PMID: 35914061.
Brownlee M. Biochemistry and molecular cell biology
of diabetic complications. Nature. 2001;414(6865):
–20. doi:10.1038/414813a
Zimny S, Schatz H, Pfohl M. The Role of Limited
Joint Mobility in Diabetic Patients With an At-Risk
Foot. Diabetes Care. 2004;27(4):942–6. doi:10.2337/
diacare.27.4.942
Allet L, Armand S, Golay A, Monnin D, De Bie RA,
De Bruin ED. Gait characteristics of diabetic patients:
a systematic review. Diabetes Metab Res Rev.
;24(3):173–91. doi:10.1002/dmrr.809
Richardson JK, Thies SB, DeMott TK, Ashton-Miller
JA. Interventions Improve Gait Regularity in Patients
with Peripheral Neuropathy While Walking on an
Irregular Surface Under Low Light. J Am Geriatr Soc.
;52(4):510–5. doi:10.1111/j.1532-5415.2004.52155.x
Cadore EL, Izquierdo M. Exercise interventions in
polypathological aging patients that coexist with
diabetes mellitus: improving functional status and
quality of life. AGE. 2015;37(3):64. doi:10.1007/s11357-
-9800-2
Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan
DW, Dempsey PC, et al. Physical Activity/Exercise
and Diabetes: A Position Statement of the American
Diabetes Association. Diabetes Care. 2016;39(11):
–79. doi:10.2337/dc16-1728
Armstrong MJ, Colberg SR, Sigal RJ. Moving
Beyond Cardio: The Value of Resistance Training,
Balance Training, and Other Forms of Exercise
in the Management of Diabetes. Diabetes Spectr.
;28(1):14–23. doi:10.2337/diaspect.28.1.14
Khurshid S, Saeed A, Kashif M, Nasreen A, Riaz H.
Effects of multisystem exercises on balance, postural
stability, mobility, walking speed, and pain in patients
with diabetic peripheral neuropathy: a randomized
controlled trial. BMC Neurosci. 2025;26(1):16.
doi:10.1186/s12868-024-00924-6
Shaffer S, Harrison A, Brown K, Brennan K. Reliability
and validity of Semmes-Weinstein Monofilament
testing in older community-dwelling adults. Journal
of Geriatric Physical Therapy. 2005 Dec 1;28(3):112-3.
Redmond AC, Crosbie J, Ouvrier RA. Development
and validation of a novel rating system for scoring
standing foot posture: The Foot Posture Index.
Clin Biomech. 2006;21(1):89–98. doi:10.1016/j.
clinbiomech.2005.08.002
Koltermann JJ, Gerber M, Beck H, Beck M. Validation
of the HUMAC balance system in comparison with
conventional force plates. Technologies. 2017 Jul
;5(3):44.
Mickle KJ, Munro BJ, Lord SR, Menz HB, Steele JR.
Foot Pain, Plantar Pressures, and Falls in Older People:
A Prospective Study. J Am Geriatr Soc. 2010;58(10):
–40. doi:10.1111/j.1532-5415.2010.03061.x
Horak FB. Postural orientation and equilibrium: what
do we need to know about neural control of balance
to prevent falls? Age Ageing. 2006;35(suppl_2):ii7–11.
doi:10.1093/ageing/afl077
Grewal GS, Schwenk M, Lee-Eng J, Parvaneh S,
Bharara M, Menzies RA, et al. Sensor-Based Interactive
Balance Training with Visual Joint Movement
Feedback for Improving Postural Stability in Diabetics
with Peripheral Neuropathy: A Randomized
Controlled Trial. Gerontology. 2015;61(6):567–74.
doi:10.1159/000371846
Akbari NJ, Naimi SS. The effect of exercise therapy
on balance in patients with diabetic peripheral
neuropathy: a systematic review. J Diabetes Metab
Disord. 2022;21(2):1861–71. doi:10.1007/s40200-022-
-1
Fried PJ, Pascual-Leone A, Bolo NR. Diabetes and
the link between neuroplasticity and glutamate in
the aging human motor cortex. Clin Neurophysiol.
;130(9):1502–10. doi:10.1016/j.clinph.2019.04.721
Fernando M, Crowther R, Lazzarini P, Sangla K,
Cunningham M, Buttner P, et al. Biomechanical
characteristics of peripheral diabetic neuropathy: A
systematic review and meta-analysis of findings from
the gait cycle, muscle activity and dynamic barefoot
plantar pressure. Clin Biomech. 2013;28(8):831–45.
doi:10.1016/j.clinbiomech.2013.08.004
Bus SA, Waaijman R, Arts M, De Haart M, Busch-
Westbroek T, Van Baal J, et al. Effect of Custom-Made
Footwear on Foot Ulcer Recurrence in Diabetes.
Diabetes Care. 2013;36(12):4109–16. doi:10.2337/dc13-
Bus SA, Maas M, De Lange A, Michels RPJ, Levi M.
Elevated plantar pressures in neuropathic diabetic
patients with claw/hammer toe deformity. J
Biomech. 2005;38(9):1918–25. doi:10.1016/j.jbiomech.
07.034
Andersen H, Nielsen S, Mogensen CE, Jakobsen
J. Muscle Strength in Type 2 Diabetes. Diabetes.
;53(6):1543–8. doi:10.2337/diabetes.53.6.1543
Ferreira JP, Sartor CD, Leal ÂMO, Sacco ICN,
Sato TO, Ribeiro IL, et al. The effect of peripheral
neuropathy on lower limb muscle strength in diabetic
individuals. Clin Biomech. 2017;43:67–73. doi:10.1016/j.
clinbiomech.2017.02.003
Churchward-Venne TA, Tieland M, Verdijk LB,
Leenders M, Dirks ML, De Groot LCPGM, et al.
There Are No Nonresponders to Resistance-Type
Exercise Training in Older Men and Women. J Am
Med Dir Assoc. 2015;16(5):400–11. doi:10.1016/j.
jamda.2015.01.071
Morrison S, Colberg SR, Mariano M, Parson HK, Vinik
AI. Balance Training Reduces Falls Risk in Older
Individuals With Type 2 Diabetes. Diabetes Care.
;33(4):748–50. doi:10.2337/dc09-1699
Lim YC, Sidarta A, Gonzalez PC, Zhang JJ, Kwong
PWH, Chua KSG. Age related alteration in EEG
evoked responses to balance perturbations on an
inclined surface. Sci Rep. 2026;16:8078. doi:10.1038/
s41598-026-39139-6
Bohannon RW, Crouch R. Minimal clinically important
difference for change in 6-minute walk test distance
of adults with pathology: a systematic review. J Eval
Clin Pract. 2017;23(2):377–81. doi:10.1111/jep.12629
PubMed PMID: 27592691.
Monteiro RL, Ferreira JSSP, Silva ÉQ, Cruvinel-Júnior
RH, Veríssimo JL, Bus SA, et al. Foot-ankle therapeutic
exercise program can improve gait speed in people
with diabetic neuropathy: a randomized controlled
trial. Sci Rep. 2022;12(1):7561. doi:10.1038/s41598-
-11745-0
Corut H, Savci S, Ozcan Kahraman B, Tanrıverdı A,
Adıyaman SC, Acar S, et al. Which field test should be
used to compare the functional exercise capacities of
patients with type 2 diabetes mellitus with and without
diabetic peripheral neuropathy? Cross-sectional
study. Endocrinol Diabetes Nutr. 2023;70(4):277–85.
doi:10.1016/j.endien.2023.02.007
Breen L, Phillips SM. Skeletal muscle protein
metabolism in the elderly: Interventions to counteract
the “anabolic resistance” of ageing. Nutr Metab.
;8(1):68. doi:10.1186/1743-7075-8-68
Kumar V, Atherton PJ, Selby A, Rankin D, Williams
J, Smith K, et al. Muscle Protein Synthetic Responses
to Exercise: Effects of Age, Volume, and Intensity.
J Gerontol A Biol Sci Med Sci. 2012;67(11):1170–7.
doi:10.1093/gerona/gls141
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